2016 ACR/EULAR 原发性干燥综合征分类
用途适用： after entry dryness criterion and exclusion screen, when classification is needed.
分层Classification aids research/structured care — not identical to clinical diagnosis alone.
局限不适用： if published exclusions (HCV, IgG4, radiation, etc.) apply. · 易错点： classifying without entry dryness/ESSDAI salivary item. · Seronegative disease still needs expert judgment.
出处Shiboski CH, et al. Arthritis Rheumatol / Ann Rheum Dis 2017 (2016 ACR/EULAR Sjögren)
本班次下一步
评完分数后：进场景连算、看相邻评分、打开对应路径。本地参考，不写入 HIS。
方法学 · 公式代入、指南要点与完整说明
适用场景
适用： after entry dryness criterion and exclusion screen, when classification is needed.
需要填写的项目
- Entry: ocular or oral dryness (≥1 of published questions) OR ESSDAI salivary-gland item ≥1 · 选项
- Exclusion criteria present (prior radiation, active HCV, AIDS, sarcoid, amyloid, GVHD, IgG4-related disease, etc.) · 选项
- Labial salivary gland: focal lymphocytic sialadenitis, focus score ≥1 · 选项
- Anti-SSA/Ro positive · 选项
- Ocular Staining Score ≥5 (or van Bijsterveld ≥4) in at least one eye · 选项
- Schirmer ≤5 mm/5 min in at least one eye · 选项
- Unstimulated whole saliva flow rate ≤0.1 mL/min · 选项
计算方法与公式
Focus-score≥1 biopsy (3) + anti-SSA (3) + OSS≥5 (1) + Schirmer≤5 (1) + UWS≤0.1 mL/min (1). Classify if ≥4.
Confirm entry and exclusions first; then sum domains.
公式代入演示
下列数值取自本工具各输入项的示例值，用本页公式在服务端实际算出，供快速核对计算过程。仅演示代入方法，不构成临床建议，也不代表任何真实病例。
| Entry: ocular or oral dryness (≥1 of published questions) OR ESSDAI salivary-gland item ≥1 | 否 |
|---|---|
| Exclusion criteria present (prior radiation, active HCV, AIDS, sarcoid, amyloid, GVHD, IgG4-related disease, etc.) | No exclusions |
| Labial salivary gland: focal lymphocytic sialadenitis, focus score ≥1 | No / not done (0) |
| Anti-SSA/Ro positive | 否 (0) |
| Ocular Staining Score ≥5 (or van Bijsterveld ≥4) in at least one eye | 否 (0) |
| Schirmer ≤5 mm/5 min in at least one eye | 否 (0) |
| Unstimulated whole saliva flow rate ≤0.1 mL/min | 否 (0) |
→ACR/EULAR SjögrenNot applicable
- Entry：Needs dryness entry (or ESSDAI salivary item)
| Entry: ocular or oral dryness (≥1 of published questions) OR ESSDAI salivary-gland item ≥1 | Yes (required) |
|---|---|
| Exclusion criteria present (prior radiation, active HCV, AIDS, sarcoid, amyloid, GVHD, IgG4-related disease, etc.) | Exclusion present — do not classify |
| Labial salivary gland: focal lymphocytic sialadenitis, focus score ≥1 | 是 (3) |
| Anti-SSA/Ro positive | 是 (3) |
| Ocular Staining Score ≥5 (or van Bijsterveld ≥4) in at least one eye | 是 (1) |
| Schirmer ≤5 mm/5 min in at least one eye | 是 (1) |
| Unstimulated whole saliva flow rate ≤0.1 mL/min | 是 (1) |
→ACR/EULAR SjögrenExcluded
- Exclusion：Classification criteria not applied when exclusions present
结果判读与分层
Classification aids research/structured care — not identical to clinical diagnosis alone.
指南要点（原创整理）
- Threshold ≥4.
- Biopsy and SSA weigh 3 each.
- 下一步： ESSDAI activity / rheumatology.
以上为依据相应指南的关键推荐、由本站用自己的语言归纳整理（非指南原文）；完整内容请见下方官方来源。
注意事项与局限
- 不适用： if published exclusions (HCV, IgG4, radiation, etc.) apply.
- 易错点： classifying without entry dryness/ESSDAI salivary item.
- Seronegative disease still needs expert judgment.
核对与出处 · 可验证治理
参考指南与出处
- [指南 / 主要来源]Shiboski CH, et al. Arthritis Rheumatol / Ann Rheum Dis 2017 (2016 ACR/EULAR Sjögren) · 来源 ↗
- CMA rheumatology Sjögren guidance on zh when cited
指南全文版权归相应学会/期刊所有；本工具仅实现其决策算法并注明出处，全文请经上方官方来源获取。
依据文献年份见参考 · 数据集整理日 2026-10-08
常见问题
常见问题
- 2016 ACR/EULAR 原发性干燥综合征分类的计算是否上传患者数据？在哪里计算？
- 计算在浏览器本地完成，输入与结果不上传服务器；结果仅供执业医师参考，须结合病史、检查与本机构方案判断，不构成诊断或处方依据。
- 2016 ACR/EULAR 原发性干燥综合征分类怎么代入计算？能举个例子吗？
- 代入: Entry: ocular or oral dryness (≥1 of published questions) OR ESSDAI salivary-gland item ≥1 否、Exclusion criteria present (prior radiation, active HCV, AIDS, sarcoid, amyloid, GVHD, IgG4-related disease, etc.) No exclusions、Labial salivary gland: focal lymphocytic sialadenitis, focus score ≥1 No / not done (0)、Anti-SSA/Ro positive 否 (0)、Ocular Staining Score ≥5 (or van Bijsterveld ≥4) in at least one eye 否 (0)、Schirmer ≤5 mm/5 min in at least one eye 否 (0)、Unstimulated whole saliva flow rate ≤0.1 mL/min 否 (0) → 结果: ACR/EULAR Sjögren Not applicable（Entry: Needs dryness entry (or ESSDAI salivary item)） 代入: Entry: ocular or oral dryness (≥1 of published questions) OR ESSDAI salivary-gland item ≥1 Yes (required)、Exclusion criteria present (prior radiation, active HCV, AIDS, sarcoid, amyloid, GVHD, IgG4-related disease, etc.) Exclusion present — do not classify、Labial salivary gland: focal lymphocytic sialadenitis, focus score ≥1 是 (3)、Anti-SSA/Ro positive 是 (3)、Ocular Staining Score ≥5 (or van Bijsterveld ≥4) in at least one eye 是 (1)、Schirmer ≤5 mm/5 min in at least one eye 是 (1)、Unstimulated whole saliva flow rate ≤0.1 mL/min 是 (1) → 结果: ACR/EULAR Sjögren Excluded（Exclusion: Classification criteria not applied when exclusions present）
核对流程与方法学
核对与依据
本工具的公式与计算方法已在本页明示、公开可逐一核查。其公式、系数与阈值依据上方「参考指南与出处」列出的权威来源核对。想了解本站对全部临床工具的核对流程与出处覆盖情况，见 临床工具核对表与方法学 →