📉 Kinetic eGFR (Chen)
UseWhen to use: rising or falling creatinine in AKI / recovery.
StrataLower KeGFR → worse instantaneous clearance than steady-state eGFR suggests.
LimitsWhen not to use: steady creatinine — use CKD-EPI/MDRD. · Pitfall: mixing µmol/L with mg/dL. · Model assumptions break with very rapid swings.
SourceChen S. Clin JASN 2013
This-shift next steps
After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.
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Methodology · worked example, guidelines & full notes
Chen kinetic GFR.
When to use
When to use: rising or falling creatinine in AKI / recovery.
How it works
KeGFR=(SSPCr×GFRbase/meanCr)×[1−24×(Cr2−Cr1)/((Cr1+Cr2)×Δt_h)].
Key points
- Chen kinetic GFR.
- Needs Δt.
- Next: volume/nephrotoxin review.
References
- Chen S. Clin JASN 2013
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Baseline / steady-state creatinine | 1.0 mg/dL |
|---|---|
| Baseline eGFR (at steady state) | 90 mL/min |
| Creatinine 1 | 1.5 mg/dL |
| Creatinine 2 | 2.0 mg/dL |
| Hours between Cr1 and Cr2 | 12 h |
→KeGFR36.7mL/min
- Mean Cr：1.75 mg/dL
- Cue：30–59 — reduced kinetic clearance band
Verification & sources · governance
FAQ
Frequently asked questions
- Does Kinetic eGFR (Chen) upload patient data? Where is it calculated?
- Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
- How is Kinetic eGFR (Chen) calculated in practice? Can you show a worked example?
- Inputs: Baseline / steady-state creatinine 1.0 mg/dL, Baseline eGFR (at steady state) 90 mL/min, Creatinine 1 1.5 mg/dL, Creatinine 2 2.0 mg/dL, Hours between Cr1 and Cr2 12 h → Result: KeGFR 36.7 mL/min（Mean Cr: 1.75 mg/dL, Cue: 30–59 — reduced kinetic clearance band）