🫘 eGFR Calculator (CKD-EPI 2021)
UseAssess and stage chronic kidney disease (with albuminuria).
StrataKDIGO G stages: G1 ≥90, G2 60–89, G3a 45–59, G3b 30–44, G4 15–29, G5 <15 mL/min/1.73 m² — combine with albumi…
LimitsEstimate only — large bias in AKI, extremes of muscle mass, amputatio… · Race-free 2021 values differ slightly from older race-inclusive equat… · Drug dosing may still use Cockcroft–Gault or labelled guidance.
SourceKDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease.…
This-shift next steps
After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.
Paste the link in Slack, Teams, X, or LinkedIn — the preview image comes from this page’s Open Graph card.
Methodology · worked example, guidelines & full notes
Race-free 2021 equation, reported per 1.73 m².
When to use
Assess and stage chronic kidney disease (with albuminuria).
How it works
CKD-EPI 2021: 142 × min(SCr/κ,1)^α × max(SCr/κ,1)^−1.200 × 0.9938^age × (1.012 if female); κ=0.7/0.9, α=−0.241/−0.302.
Key points
- Race-free 2021 equation, reported per 1.73 m².
- Confirm eGFR < 60 over ≥ 3 months for CKD.
- Combine with albuminuria for KDIGO category.
References
- [Guideline / primary source]KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. doi:10.1016/j.kint.2023.10.018
- [Guideline / primary source]European layer (cardiovascular and CKD management reference): 2026 ESC Guidelines for the management of cardiovascular disease and chronic kidney disease, in collaboration with the European Renal Association (ERA) (Damman K, et al. Eur Heart J. Published online August 28, 2026. doi:10.1093/eurheartj/ehag098). It recommends staging with a validated creatinine-based eGFR equation, confirming chronicity with two eGFR and uACR measurements at least 3 months apart, and considering cystatin C–based eGFR when needed. For European populations it prefers the 2009 CKD-EPI equation without the race coefficient, so it is not the basis for the equation on this page. This page keeps CKD-EPI 2021 within the KDIGO 2024 framework; the equation and stage cut-offs are unchanged.
- Inker LA, et al. CKD-EPI 2021. N Engl J Med 2021
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Serum creatinine | 1.0 |
|---|---|
| Creatinine unit | mg/dL |
| Age | 60 years |
| Sex | Male |
→eGFR86mL/min/1.73m²
- Creatinine used：1 mg/dL
- CKD GFR category：G2 (60–89)
- Equation：CKD-EPI 2021 (creatinine, race-free)
| Serum creatinine | 80 |
|---|---|
| Creatinine unit | µmol/L |
| Age | 60 years |
| Sex | Female |
→eGFR73mL/min/1.73m²
- Creatinine used：80 µmol/L
- CKD GFR category：G2 (60–89)
- Equation：CKD-EPI 2021 (creatinine, race-free)
Verification & sources · governance
FAQ
Frequently asked questions
- Does eGFR Calculator (CKD-EPI 2021) upload patient data? Where is it calculated?
- Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
- How is eGFR Calculator (CKD-EPI 2021) calculated in practice? Can you show a worked example?
- Inputs: Serum creatinine 1.0, Creatinine unit mg/dL, Age 60 years, Sex Male → Result: eGFR 86 mL/min/1.73m²（Creatinine used: 1 mg/dL, CKD GFR category: G2 (60–89), Equation: CKD-EPI 2021 (creatinine, race-free)） Inputs: Serum creatinine 80, Creatinine unit µmol/L, Age 60 years, Sex Female → Result: eGFR 73 mL/min/1.73m²（Creatinine used: 80 µmol/L, CKD GFR category: G2 (60–89), Equation: CKD-EPI 2021 (creatinine, race-free)）