🩸 CKD Anemia of Renal Disease Management
UseUse to decide on iron supplementation, ESA or HIF-PHI initiation, avoiding a rapid Hb rise.
StrataThe Hb upper target is hidden: it conflicts with KDIGO 2025 (PMID 42735412; ESA maintenance Hb <115 g/L). [Pe…
SourceHedayati SS, et al. Ann Intern Med 2026 (KDIGO 2025 anemia guideline synopsis, PMID 42735412)
This-shift next steps
After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.
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Methodology · worked example, guidelines & full notes
Iron deficiency and reversible factors are corrected before starting an ESA, and an excessively rapid hemoglobin rise is avoided. (original synthesis · not guideline verbatim)
When to use
Use to decide on iron supplementation, ESA or HIF-PHI initiation, avoiding a rapid Hb rise.
How it works
Iron deficiency (thresholds [pending update]) → correct iron first, then start ESA/HIF-PHI; avoid an overly rapid Hb rise.
Key points
- Iron deficiency and reversible factors are corrected before starting an ESA, and an excessively rapid hemoglobin rise is avoided. (original synthesis · not guideline verbatim)
- Hemodialysis uses a higher ferritin threshold than non-dialysis/PD.
References
- [Guideline / primary source]Hedayati SS, et al. Ann Intern Med 2026 (KDIGO 2025 anemia guideline synopsis, PMID 42735412)
- [Guideline / primary source]Kidney Disease: Improving Global Outcomes (KDIGO). KDIGO Clinical Practice Guideline for Anemia in CKD. Kidney Int Suppl 2012.
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Hemoglobin Hb | 95 g/L |
|---|---|
| Serum ferritin SF | 120 ng/mL |
| Transferrin saturation TSAT | 18 % |
| Dialysis modality | Non-dialysis / peritoneal dialysis |
→DispositionStart anemia correction
- Iron status & supplementation：Iron deficiency present (non-dialysis/PD): give iron first (oral or IV for non-dialysis, usually IV for dialysis; avoid IV iron in active infection/bacteremia)
- ESA/HIF-PHI：Start an erythropoiesis-stimulating agent (ESA, first-line) or HIF-PHI (roxadustat): correct iron deficiency and reversible factors (inflammation, bleeding, nutrition, etc.) and exclude other anemia causes first
- Target：avoid an overly rapid Hb rise (magnitude [pending update])
Verification & sources · governance
FAQ
Frequently asked questions
- What are the limits and cautions when using CKD Anemia of Renal Disease Management?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- Does CKD Anemia of Renal Disease Management upload patient data? Where is it calculated?
- Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
- How is CKD Anemia of Renal Disease Management calculated in practice? Can you show a worked example?
- Inputs: Hemoglobin Hb 95 g/L, Serum ferritin SF 120 ng/mL, Transferrin saturation TSAT 18 %, Dialysis modality Non-dialysis / peritoneal dialysis → Result: Disposition Start anemia correction（Iron status & supplementation: Iron deficiency present (non-dialysis/PD): give iron first (oral or IV for non-dialysis, usually IV for dialysis; avoid IV iron in active infection/bacteremia), ESA/HIF-PHI: Start an erythropoiesis-stimulating agent (ESA, first-line) or HIF-PHI (roxadustat): correct iron deficiency and reversible factors (inflammation, bleeding, nutrition, etc.) and exclude other anemia causes first, Target: avoid an overly rapid Hb rise (magnitude [pending update])）