影像引导下硬膜外类固醇注射实践参数
本文为美国放射学会联合多个学术组织修订的影像引导下硬膜外类固醇注射实践参数。该参数适用于保守治疗无效的脊髓疼痛及神经根病患者,评估疗效与安全性并提供最佳实践建议。
要点
- 硬膜外类固醇注射须在影像引导下进行,操作者需熟悉脊柱解剖
- FDA警示该操作存在罕见但严重的神经系统风险
- 建议将注射纳入多学科治疗路径而非单独使用
核心结论
- 该参数针对适应证、禁忌证、患者选择及技术操作提出建议,以优化硬膜外类固醇注射疗效并降低严重神经及其他并发症风险。
研究设计与样本
- 由美国放射学会实践参数委员会及介入与心血管放射学委员会联合ABS、ACNM、ARS、SIR、SNMMI协作修订。
- 修订过程遵循ACR网站Process for Developing ACR Practice Parameters and Technical Standards所描述的方法。
诊断标准与关键数值
- 对于经适当选择的颈痛和腰痛患者,尤其存在退行性改变或神经根病时,硬膜外类固醇注射可带来疼痛、活动能力、功能及生活质量的显著改善。
- 本参数明确了绝对禁忌证与相对禁忌证。
- 建议仅由经过适当培训并具备资质的医生操作,操作者须理解适应证、相关药理学及并发症处理。
临床应用与阅片要点
- 硬膜外类固醇注射须在影像引导下进行,操作技术须细致并具备详尽的脊柱解剖知识。
- 鉴于FDA强调的罕见但严重神经系统风险,操作时应格外重视安全性。
- 建议将硬膜外类固醇注射纳入多学科治疗路径,而非作为独立治疗。
以上解读依据论文摘要(全文未开放获取或许可不允许翻译转载)。
英文原文(摘要)· 点击展开
AIM/OBJECTIVES/BACKGROUND: The practice parameter was revised collaboratively by the American College of Radiology (ACR), the American Brachytherapy Society (ABS), the American College of Nuclear Medicine (ACNM), the American Radium Society (ARS), the Society of Interventional Radiology (SIR), and the Society of Nuclear Medicine and Molecular Imaging (SNMMI). Epidural steroid injections (ESI) are widely used procedures for managing spinal pain and radiculopathy in patients who do not respond to conservative therapy. This multidisciplinary practice parameter reviews evidence for the efficacy and safety of ESI and provides best practice recommendations.
METHODS: This practice parameter was revised according to the process described under the Process for Developing ACR Practice Parameters and Technical Standards on the ACR website (https://www.acr.org/Clinical-Resources/Clinical-Tools-and-Reference/Practice-Parameters-and-Technical-Standards) by the Committee on Practice Parameters - Interventional and Cardiovascular Radiology of the ACR Commission on Interventional and Cardiovascular, Committee on Practice Parameters and Technical Standards - Nuclear Medicine and Molecular Imaging of the ACR Commission on Nuclear Medicine and Molecular Imaging and the Committee on Practice Parameters - Radiation Oncology of the ACR Commission on Radiation Oncology in collaboration with the ABS, the ACNM, the ARS, the SIR, and the SNMMI.
RESULTS: Epidural steroid injections can provide meaningful improvements in pain, mobility, function, and quality of life for appropriately selected patients with neck and low back pain, particularly when degenerative changes or radiculopathy are present. This document advises that ESI be performed with image guidance, meticulous technique, and detailed knowledge of spinal anatomy, particularly in light of rare but serious neurologic risks highlighted by the FDA. The parameter specifies absolute and relative contraindications, encourages integrating ESI within a multidisciplinary care pathway rather than as stand-alone therapy, and recommends that only appropriately trained and credentialed physicians who understand the indications, relevant pharmacology, and complication management perform these procedures.
CONCLUSIONS: This multidisciplinary practice parameter provides recommendations on indications, contraindications, patient selection, and technical execution to optimize the therapeutic benefit of epidural steroid injections while reducing the risk of serious neurologic and other complications.
引用
- Blackham, Amrhein, Barr, et al. ACR-ASNR-ASSR-SIR-SNIS Practice Parameter for the Performance of Image-Guided Epidural Steroid Injection. AJNR Am J Neuroradiol. 2026. PMID: 42235968. doi:10.3174/ajnr.A9280
供执业医师工作参考,不替代临床判断;数值与分级以指南原文为准。