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胰腺囊性病变再审视:日常实践中的形态学模式与诊断陷阱

Pancreatic cystic lesions revisited: morphologic patterns and diagnostic pitfalls in daily practice.
PubMed 文献 · Abdom Radiol (NY) · 2026-05-15

本文综述了胰腺囊性病变的形态学解读框架,强调导管沟通、内部结构、壁结节或实性成分等特征与病理基础及临床意义的关系。文章通过代表性病例展示常见囊性肿瘤及其变异型的典型表现,并重点讨论实性肿瘤囊性变等模仿病变的诊断陷阱,提出整合形态学模式、强化特征、导管解剖及辅助影像发现以提高诊断准确性。

要点

  • 以形态学模式(导管沟通、内部结构、壁结节/实性成分)作为结构化解读框架。
  • 注意实性肿瘤囊性变(神经内分泌肿瘤、实性假乳头状肿瘤、胰腺导管腺癌)可模仿真性囊性病变。
  • 整合强化特征、导管解剖及辅助影像发现,避免仅凭囊性外观误判。

核心结论

  • 基于形态学模式的系统分析结合强化特征、导管解剖和辅助影像发现,有助于准确区分胰腺囊性病变并识别模仿病变。

研究设计与样本

  • 本文为综述,围绕胰腺囊性病变的形态学模式与诊断陷阱进行文献汇总与病例图示,未报告系统检索范围、纳入文献数量或证据分级。

关键影像表现/征象

  • 导管沟通、内部结构以及壁结节或实性成分的存在是胰腺囊性病变的关键形态学特征。
  • 常见囊性肿瘤包括浆液性囊性肿瘤、黏液性囊性肿瘤和导管内乳头状黏液性肿瘤及其变异型,具有各自的特征性表现。
  • 实性肿瘤囊性变(如神经内分泌肿瘤、实性假乳头状肿瘤和胰腺导管腺癌)可酷似真性囊性病变,但处理方式根本不同。

临床应用与阅片要点

  • 阅片时先评估病变与胰管是否沟通、内部结构(单房/多房/蜂窝状)及有无壁结节或实性成分。
  • 对囊性外观病变需结合强化方式、导管解剖和辅助影像发现,警惕实性肿瘤囊性变等模仿病变。
  • 报告应描述上述形态学特征,为风险分层和临床管理提供依据。

局限性

  • 本文为综述,未报告系统检索策略、纳入文献数量及证据等级,结论基于叙述性汇总。

以上解读依据论文摘要(全文未开放获取或许可不允许翻译转载)。

英文原文(摘要)· 点击展开

The increasing use of cross-sectional imaging has led to more frequent incidental detection of pancreatic cystic lesions, presenting diagnostic challenges for radiologists. These lesions encompass a heterogeneous spectrum ranging from benign cysts to premalignant and malignant neoplasms, often with overlapping imaging features. Accurate imaging-based characterization is therefore essential for risk assessment and clinical management. This review presents a morphology-based approach to pancreatic cystic lesions, emphasizing morphologic imaging patterns as a practical framework for structured interpretation. Key features-including ductal communication, internal architecture, and the presence of mural nodules or solid components-are discussed in relation to their pathologic basis and clinical implications. Representative examples illustrate the characteristic appearances of common cystic neoplasms, including serous cystic neoplasm, mucinous cystic neoplasm, and intraductal papillary mucinous neoplasm, along with their variants. Particular attention is given to diagnostic pitfalls and mimickers, such as cystic degeneration of solid tumors including neuroendocrine tumors, solid pseudopapillary neoplasms, and pancreatic ductal adenocarcinoma, which may closely resemble true cystic lesions but require fundamentally different management. Through illustrative cases, this review highlights the importance of integrating morphologic pattern analysis with enhancement characteristics, ductal anatomy, and ancillary imaging findings. Recognition of these patterns and potential pitfalls is essential for accurate interpretation and clinically meaningful guidance.

来源:Abdom Radiol (NY),查看原文。版权归原作者所有。

引用

  1. Tamura A, Mukaida E, Kirita K, et al. Pancreatic cystic lesions revisited: morphologic patterns and diagnostic pitfalls in daily practice. Abdom Radiol (NY). 2026. PMID: 42138742. doi:10.1007/s00261-026-05552-8

供执业医师工作参考,不替代临床判断;数值与分级以指南原文为准。