文献速递胸痛与 ACS

腔内影像评估动脉粥样硬化及指导经皮冠状动脉介入治疗

Intracoronary imaging to assess atherosclerosis and to guide percutaneous coronary intervention.
PubMed 文献 · Eur Heart J · 2026-10-16

本文综述腔内影像(血管内超声IVUS和光学相干断层扫描OCT)在评估冠脉粥样硬化及指导经皮冠状动脉介入治疗(PCI)中的当代证据。基于近期随机对照试验和指南推荐,影像引导PCI可减少主要不良心脏事件,尤其适用于复杂病变和高危患者。文章还讨论了腔内影像的优势、局限和未来研究方向。

要点

  • 腔内影像可高分辨率评估冠脉粥样硬化,并指导PCI。
  • 影像引导PCI可降低主要不良心脏事件,尤其用于复杂病变。
  • IVUS和OCT适用于左主干、分叉、钙化、长病变及ACS患者。

核心结论

  • 腔内影像已成为体内评估冠脉粥样硬化及指导PCI的重要工具,影像引导PCI在复杂病变中可改善临床结局。

研究设计与样本

  • 本综述为当代综述,综合近期随机对照试验数据和当前指南推荐。

主要发现

  • 多项随机对照试验显示,影像引导PCI可降低主要不良心脏事件(心源性死亡、心肌梗死和再次血运重建),尤其在复杂临床和解剖情况。

关键数值与推荐

  • 推荐使用血管内超声(IVUS)或光学相干断层扫描(OCT)指导PCI,以减少主要不良心脏事件。
  • 特别推荐用于左主干病变、复杂分叉病变、钙化病变、长病变及急性冠脉综合征等高危患者。

临床怎么用

  • 在复杂病变和ACS患者中,可优先选用IVUS或OCT进行高分辨率评估,以精确确定支架尺寸和优化介入策略。

局限性

  • 本文讨论了腔内影像的局限性及未解决问题,并指出未来应进一步研究以改善患者预后。

以上解读依据论文摘要(全文未开放获取或许可不允许翻译转载)。

原文

Intracoronary imaging has become an important tool for the in vivo assessment of coronary atherosclerosis and for guiding percutaneous coronary intervention. By enabling high-resolution visualization of coronary anatomy, these modalities allow for more accurate lesion characterization, precise stent sizing, and optimized procedural strategies. In recent years, multiple randomized controlled trials have demonstrated that imaging-guided percutaneous coronary intervention reduces major adverse cardiac events (including cardiac death, myocardial infarction, and repeat revascularization), particularly in complex clinical and anatomical settings. This state-of-the-art review synthesizes contemporary evidence supporting the use of intravascular ultrasound and optical coherence tomography to guide percutaneous coronary intervention and improve clinical outcomes, drawing from recent trial data and current guideline recommendations. Special emphasis is placed on complex lesion subsets, such as left main coronary artery disease and other complex bifurcation lesions, calcified lesions, long lesions, and scenarios involving patients at heightened risk, such as those with acute coronary syndrome. Finally, this review considers the strengths and limitations of intracoronary imaging, as well as unresolved questions and priority areas for future research aimed at further improving patient outcomes.

来源:Eur Heart J,查看原文。版权归原作者所有。

引用

  1. Vergallo, Stone, Johnson, et al. Intracoronary imaging to assess atherosclerosis and to guide percutaneous coronary intervention. Eur Heart J. 2026. PMID: 42880972. doi:10.1093/eurheartj/ehag824

供执业医师工作参考,不替代临床判断;数值与分级以指南原文为准。