指南与共识哮喘急性发作

2024年BTS/NICE/SIGN哮喘指南有潜力改善英国哮喘结局,但需立即行动

2024 BTS/NICE/SIGN asthma guidelines have the potential to improve UK asthma outcomes, but we must act now
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本文基于已发表文献与专家共识,讨论2024年英国胸科学会(BTS)、国家健康与临床优化研究所(NICE)和苏格兰校际指南网络(SIGN)联合发布的哮喘指南。指南推荐以抗炎缓解剂为基础的哮喘管理策略,有望显著改善英国哮喘结局,但实施面临知识行动差距及系统和个人层面的障碍。

要点

  • 英国哮喘结局在欧洲最差,与短效β2激动剂过度使用和含吸入性皮质类固醇吸入器使用不足相关。
  • 新指南推荐以抗炎缓解剂为基础的哮喘管理方法。
  • 实施需克服知识行动差距以及系统和个人层面的障碍。

核心结论

  • 2024年BTS/NICE/SIGN联合哮喘指南推荐以抗炎缓解剂为基础的哮喘管理方法,有潜力显著改善英国哮喘结局,但需立即采取行动应对实施障碍。

研究设计与样本

  • 基于已发表文献和专家共识的指南相关讨论,聚焦实施挑战与知识行动差距。

主要发现

  • 英国哮喘结局在欧洲最差。
  • 短效β2激动剂过度使用和含吸入性皮质类固醇吸入器使用不足与哮喘加重和死亡风险相关。
  • 指南实施存在知识行动差距,系统和个人层面均面临挑战。

关键数值与推荐

  • 指南推荐以抗炎缓解剂为基础的哮喘管理方法。

临床怎么用

  • 实施指南时需同时应对系统和个人层面的障碍,以减少知识行动差距并落实抗炎缓解剂策略。

局限性

  • 实施过程中存在知识行动差距,可能阻碍指南在实践中的应用。
  • 系统和个人层面的实施挑战尚未完全解决。

以上解读依据论文摘要(全文未开放获取或许可不允许翻译转载)。

原文

WHAT IS ALREADY KNOWN ON THIS TOPIC Asthma is a common lung disease and outcomes in the UK are among the worst in Europe. The overuse of short-acting beta agonist and underuse of anti-inflammatory, inhaled corticosteroid-containing inhalers are associated with risk of exacerbations and death. The new collaborative British Thoracic Society(BTS), National Institute for Health and Care Excellence (NICE), Scottish Intercollegiate Guideline Network (SIGN) Asthma Guideline endorses an anti-inflammatory reliever-based approach to asthma management and has potential to significantly improve asthma outcomes in the UK. WHAT THIS STUDY ADDS We discuss the role of guidelines to support delivery of evidence-based practice and highlight the knowledge-action gap that can prevent implementation of guidelines in practice. Based on the published literature and expert consensus, we describe some of the challenges/barriers that will be faced at both a system and individual level when implementing the BTS, NICE, SIGN...

来源:Thorax,查看原文。版权归原作者所有。

引用

  1. Thorax:2024 BTS/NICE/SIGN asthma guidelines have the potential to improve UK asthma outcomes, but we must act now

供执业医师工作参考,不替代临床判断;数值与分级以指南原文为准。