通过循证健康信息提升肺栓塞患者健康素养的可行性研究
该研究纳入116例住院肺栓塞患者，随机分为提供循证健康信息手册的干预组与对照组，评估可行性及健康素养改善效果。随访4个月后，干预组在「处理肺栓塞相关健康信息」领域得分显著提高（3.86 vs 3.43，p=0.030），肺栓塞相关知识正确率更高（45% vs 17%达≥2项正确，p=0.007），且信息充分感更强（6.00 vs 4.14，p<0.001）。
要点
- 提供循证健康信息手册在肺栓塞患者中可行，且可能提升疾病特异性健康素养。
- 干预组处理肺栓塞相关健康信息的能力及知识正确率显著优于对照组。
- 患者认为手册易获取、可信，并能从他人叙事中获得情感支持。
核心结论
- 通过手册提供循证健康信息是可行的，可能增强肺栓塞特异性健康素养和患者知识。
研究设计与样本
- 可行性随机对照研究，住院期间招募肺栓塞患者，干预组提供循证健康信息手册，对照组无手册，基线与肺栓塞后4个月完成问卷。
主要发现
- 干预组在「处理肺栓塞相关健康信息」领域得分显著高于对照组（3.86 vs 3.43，p=0.030，r=0.30）。
- 干预组肺栓塞相关知识正确率更高（45% vs 17%达≥2项正确，p=0.007，Cramer's V=0.29）。
- 干预组信息充分感更强（6.00 vs 4.14，p<0.001，r=0.50）。
- 定性访谈显示手册主要在急性期后阶段使用，患者评价其易获取、可信，并能从他人叙事中获得情感支持。
临床怎么用
- 可考虑向住院肺栓塞患者提供循证健康信息手册以辅助提升健康素养和疾病知识。
- 手册内容可包含患者叙事以提供情感支持，并关注急性期后的使用需求。
局限性
- 本研究为可行性研究，样本量有限，随访应答率为65%，脱落可能影响结果解释。
- 原文指出在分发策略和有效实施方面仍存在挑战。
以上解读依据论文摘要（全文未开放获取或许可不允许翻译转载）。
原文
Front Public Health. 2026 May 13;14:1814447. doi: 10.3389/fpubh.2026.1814447. eCollection 2026. ABSTRACT BACKGROUND: Pulmonary embolism (PE) is a common condition with significant physical and psychological impairments. This study was intended to examine the feasibility of how evidence-based health information on PE in the form of a brochure can be distributed and used to strengthen PE-specific health literacy. MATERIALS AND METHODS: Patients with PE were recruited during their hospital stay and were randomized in an intervention group which was provided with the brochure and a control group. Questionnaires were completed at baseline and four months after PE. Primary focus of the study were feasibility metrics such as recruitment and dropout rates, suitability of randomization processes, and the acceptance of the intervention. Health literacy was assessed using the Health Literacy Pulmonary Embolism (HeLP) questionnaire to gather information about expected effect sizes of the intervention. Further patient-oriented and information-related outcomes (e.g., health-related quality of life, mental well-being, communication with treating physicians and relatives) were assessed as secondary outcomes during follow-up. Additional qualitative interviews in the intervention group were conducted for further information on acceptance and usage patterns of the brochure. RESULTS: At baseline, 116 of 249 hospitalized patients with PE were enrolled in the study. Seventy-five participants (intervention: 33, control: 42) completed the follow-up, representing a response rate of 65%. PE-specific health literacy was significantly improved in the domain 'dealing with PE-related health information' in the intervention group (3.86 vs. 3.43, p = 0.030, r = 0.30). Participants of the intervention group showed also better PE-related knowledge compared to the control group (45% vs. 17% with ≥ 2 correct items, p = 0.007, Cramer's V = 0.29) and a stronger feeling of being informed (6.00 vs. 4.14, p < 0.001, r = 0.50). Qualitative interviews underlined predominant usage of the brochure during post-acute phase. Patients rated the patient information as easily accessible and as a trustworthy source and highlighted the emotional support through narratives of other patients. CONCLUSION: Provision of evidence-based health information via a brochure is feasible and may enhance PE-specific health literacy and patient knowledge. Challenges regarding distribution strategies, effective implementati
引用
- PubMed 高证据 · 肺栓塞：Improving health literacy of patients with pulmonary embolism through evidence-based health information: a feasibility study
供执业医师工作参考，不替代临床判断；数值与分级以指南原文为准。