三种心理社会因素对高危人群肺癌筛查依从性的影响
研究基于2022年BRFSS调查中32,640名50至79岁肺癌高危个体，分析生活满意度、必要情感支持和感知社会隔离与肺癌筛查（LCS）的关系。过去12个月内3243人（9.9%）接受LCS；控制变量后，对生活满意者比非常满意者LCS使用概率高19%，从未经历社会隔离者比总是经历社会隔离者LCS使用概率低30.1%。
要点
- 高危人群中仅9.9%在过去12个月接受肺癌筛查。
- 对生活非常满意者肺癌筛查使用概率反而更低。
- 从未经历社会隔离者肺癌筛查使用概率更低。
核心结论
- 应更关注对生活非常满意或未经历社会隔离的肺癌高危个体，未来策略需整合心理社会因素以提高筛查依从性。
研究设计与样本
- 研究利用2022年行为风险因素监测系统（BRFSS）调查数据，纳入32,640名50至79岁肺癌高危个体。
- 采用描述性统计、Wald设计卡方检验和两个多变量逻辑回归模型分析心理社会因素对LCS的影响，并使用复杂抽样权重。
主要发现
- 32,640名符合LCS条件参与者中，3243人（9.9%）在过去12个月到医院接受LCS。
- 控制变量后，对生活满意者比非常满意者LCS使用概率高19%。
- 从未经历社会隔离者比总是经历社会隔离者LCS使用概率低30.1%。
临床怎么用
- 在肺癌筛查推广中，需识别并关注对生活非常满意或未经历社会隔离的高危个体，将其作为靶向干预重点人群。
以上解读依据论文摘要（全文未开放获取或许可不允许翻译转载）。
原文
Sci Rep. 2026 Apr 17;16(1):17892. doi: 10.1038/s41598-026-48951-z. ABSTRACT Psychosocial factors have a significant impact on the promotion of preventive health behaviors in populations. This study aimed to examine the relationship between lung cancer screening (LCS) and three specific psychosocial factors: life satisfaction, necessary emotional support, and perceived social isolation, among a nationally representative sample. We utilized data from the 2022 Behavioral Risk Factor Surveillance System (BRFSS) survey, which included 32,640 individuals aged 50 to 79 years who were at high risk for lung cancer. Descriptive statistics and Wald’s design-based chi-squared tests analyzed demographic and socioeconomic characteristics’ relationship with LCS. The two multivariate logistic regression models to estimate the influence of three psychosocial factors on LCS. All models were calculated utilizing the complex survey weights from the BRFSS, with statistical analyses performed using R version 4.3.3. We found that 3243 (9.9%) of the 32,640 LCS-eligible participants went to the hospital for an LCS in the past 12 months. After controlling control variables, participants who were satisfied with their lives had a 19% higher probability of LCS use than participants who were very satisfied with their lives. In addition, Participants who never experienced social isolation were 30.1% less likely to use the LCS than those who always experienced social isolation. Our study demonstrated that greater attention should be given to high-risk lung cancer individuals who are very satisfied with their lives or have not experienced social isolation. Future strategies should integrate these psychosocial elements to develop targeted interventions aimed at increasing LCS adherence. PMID: 41998073 | PMC: PMC13250159 | DOI: 10.1038/s41598-026-48951-z
引用
- 指南共识 · 肺结节与肺癌筛查：The role of three important psychosocial factors on adherence to lung cancer screening recommendations in high-risk populations
供执业医师工作参考，不替代临床判断；数值与分级以指南原文为准。