文献速递异位妊娠与早孕出血

腹腔镜保留子宫技术治疗宫颈阴道发育不全伴功能性子宫残腔

A Uterus‐Preserving Laparoscopic Technique for Cervicovaginal Agenesis With Functional Uterine Remnants
RSS 订阅 · BJOG · 2026-09-02

本文报告一种保留子宫的腹腔镜技术,用于治疗宫颈阴道发育不全伴功能性子宫残腔的罕见苗勒管畸形患者。该技术联合腹膜下拉阴道成形术与导管引导的子宫阴道吻合术,2019年至2024年间应用于7例患者。结果显示所有患者恢复经血引流,吻合口通畅,无术中膀胱、直肠、输尿管或血管并发症。

要点

  • 该技术适用于经严格选择的宫颈阴道发育不全伴功能性子宫残腔患者。
  • 术后需使用模具和宫内导管维持吻合口通畅。
  • 吻合口通畅不代表子宫生物学功能、着床潜能或妊娠安全性正常。

核心结论

  • 腹腔镜腹膜下拉阴道成形术联合导管引导子宫阴道吻合术可在经严格选择的患者中恢复经血引流和解剖通畅。

研究设计与样本

  • 单中心病例系列报告,纳入2019年至2024年间接受腹腔镜重建的7例宫颈阴道发育不全伴功能性子宫残腔患者。
  • 手术包括腹腔镜引导下膀胱直肠间隙分离、腹膜下拉阴道成形术、梗阻子宫残腔切开引流、宫内Foley导管置入及环周子宫阴道吻合。
  • 双侧残腔患者先行腔隙融合再行吻合,术后使用模具和宫内导管维持愈合期通畅。

主要发现

  • 所有患者均恢复经血引流,门诊宫腔镜确认子宫阴道吻合口通畅且子宫内膜腔可探及。
  • 术中无膀胱、直肠、输尿管或血管并发症发生。
  • 1例患者经历两次冻融胚胎移植失败,1例患者因复发性盆腔炎需行子宫切除但保留新阴道。
  • 可获得随访期间未观察到晚期狭窄。

关键数值与推荐

  • 适应证为宫颈阴道发育不全伴功能性子宫残腔导致的经血流出受阻。

临床怎么用

  • 该技术为经严格选择的宫颈阴道发育不全伴功能性子宫残腔患者提供了一种可行的保留子宫方案。

局限性

  • 样本量小且生殖随访有限,结果解读需谨慎。
  • 可探及的腔道不能证明子宫生物学功能、着床潜能或妊娠安全性正常。

以上解读依据论文摘要(全文未开放获取或许可不允许翻译转载)。

原文

ABSTRACT Background Cervicovaginal agenesis with functional uterine remnants is a rare Müllerian anomaly that may cause obstructed menstrual flow, pelvic pain, haematometra, haematosalpinx and endometriosis. Uterus-preserving reconstruction is challenging because it requires both neovaginal creation and durable uterine drainage. Aims To describe a uterus-preserving laparoscopic technique combining peritoneal pull-down neovaginoplasty with catheter-guided uterovaginal anastomosis in patients with cervicovaginal agenesis and obstructed functional uterine remnants. Materials and Methods Seven patients with cervicovaginal agenesis and functional uterine remnants underwent laparoscopic reconstruction between 2019 and 2024. The procedure included laparoscopic-guided vesicorectal dissection, peritoneal pull-down neovaginoplasty, opening and drainage of the obstructed uterine remnant, intrauterine Foley catheter placement and circumferential uterovaginal anastomosis. In patients with bilateral remnants, cavity unification was performed before anastomosis. Postoperative mould use and intrauterine catheterisation were used to maintain patency during healing. Results Menstrual drainage was restored in all patients. Office hysteroscopy confirmed a patent uterovaginal anastomosis and accessible endometrial cavity. No intraoperative bladder, rectal, ureteric or vascular complications occurred. One patient underwent two unsuccessful frozen embryo transfer attempts. One patient required hysterectomy for recurrent pelvic inflammatory disease, with preservation of the neovagina. No late stenosis was observed during available follow-up. Discussion This technique may provide a feasible uterus-preserving approach for selected patients with cervicovaginal agenesis and functional uterine remnants. However, the presence of an accessible cavity does not prove normal biological uterine function, implantation potential or pregnancy safety. The findings should be interpreted with caution because of the small sample size and limited reproductive follow-up. Conclusion Laparoscopic peritoneal pull-down neovaginoplasty combined with catheter-guided uterovaginal anastomosis may restore menstrual drainage and anatomical patency in carefully selected patients. Further multicentre experience with objective imaging, hysteroscopic follow-up and reproductive outcome data is required to assess fertility potential, pregnancy safety and long-term durability.

来源:BJOG,查看原文。版权归原作者所有。

引用

  1. BJOG:A Uterus‐Preserving Laparoscopic Technique for Cervicovaginal Agenesis With Functional Uterine Remnants

供执业医师工作参考,不替代临床判断;数值与分级以指南原文为准。