科研动态期刊摘要
[评论] 从PROSpect到临床：背景与病理生理学考量
The Lancet · 2026-10-30
摘要
儿童急性呼吸窘迫综合征（PARDS）是儿童直接或间接肺损伤的常见且严重的表现。治疗重点在于谨慎实施肺保护策略，高频振荡通气（HFOV）和俯卧位通气常用于最严重的病例。因此，我们以极大兴趣阅读了Martha A Q Curley及其同事发表在《柳叶刀》上的关于早期儿童急性呼吸窘迫综合征中俯卧位通气与高频振荡通气的PROSpect试验。
English
[Comment] From PROSpect to the bedside: contextual and pathophysiological considerations
Paediatric acute respiratory distress syndrome (PARDS) is a common, severe manifestation of direct or indirect lung injury in children. Management focuses on the careful implementation of lung protective strategies with high-frequency oscillatory ventilation (HFOV) and prone positioning often deployed in the most severe cases. As such, we read the Prone positioning and high-frequency oscillatory ventilation in early paediatric acute respiratory distress syndrome (PROSpect) trial by Martha A Q Curley and colleagues published in The Lancet with great interest.