化疗患者中的虚拟社交互动与心理资本：一项随机对照试验。
完整摘要 · 中文译文
背景：与癌症相关的心理困扰在全球范围内仍未得到充分解决。虚拟干预提供了有前景的替代方案，但缺乏其在化疗患者中增强心理资本（PsyCap）的证据。 目的：本研究旨在评估虚拟社交互动干预对接受化疗患者心理资本的有效性。 方法：这项单盲随机对照试验（RCT）纳入了伊朗马赞达兰省拉姆萨尔市伊玛目萨贾德医院肿瘤科住院的76名化疗患者。参与者通过便利抽样法选取，然后采用奇偶（交替）分配法分配到干预组或对照组。干预组参加了为期6周的虚拟社交互动，包括每周上传至伊朗消息平台（Eitaa）的异步材料（录制音频、短视频、图片、PDF和PowerPoint文件），以及在Skyroom平台上进行的实时同步小组会议，每次会议至少10名参与者。对照组接受常规护理。使用Luthans心理资本问卷在基线和干预后测量心理资本。协方差分析（ANCOVA）模型（A/B）对基线评分和年龄进行了调整。 结果：干预组在所有结局指标上均有所改善，心理资本总分增加了23.6分。各分量显著增加：自我效能感增加5.8分，心理韧性增加5.8分，希望增加5.5分，乐观增加6.5分（p < 0.0001）。协方差分析模型证实了上述结 在校正基线评分和年龄后，效应显著（Δ SMD > 1）。 结论：虚拟社交互动显著增强化疗患者的心理资本（PsyCap）。然而，要自信地推广这些发现并提出建议，需要在更大规模、多中心的试验中进行类似研究并重复验证。
完整摘要 · 英文原文
BACKGROUND: Cancer-related psychological distress remains underaddressed globally. Virtual interventions offer promising alternatives but lack evidence for enhancing Psychological Capital (PsyCap) in chemotherapy patients. OBJECTIVE: This study aimed to evaluate the efficacy of a virtual social interaction intervention on PsyCap in patients undergoing chemotherapy. METHODS: This single-blind randomized controlled trial (RCT) enrolled 76 chemotherapy patients hospitalized in the oncology ward of Imam Sajjad Hospital, Ramsar, Mazandaran, Iran. Participants were selected via convenience sampling and then allocated to intervention or control groups using an odd-even (alternating) assignment method. The intervention group participated in 6 weeks of virtual social interactions, consisting of asynchronous materials (recorded audio, short videos, images, PDF, and PowerPoint files) uploaded weekly to Iranian messaging platforms (Eitaa), as well as live synchronous group sessions conducted on the Skyroom platform with a minimum of 10 participants per session. The control group received standard care. The PsyCap was measured using Luthans' Psychological Capital Questionnaire at both baseline and post-intervention. The Analysis of Covariance (ANCOVA) models (A/B) were adjusted for baseline scores and age. RESULTS: The intervention group showed improvements across all outcomes, with the total PsyCap score increasing by 23.6 points. Components significantly increased: self-efficacy by 5.8 points, resilience by 5.8, hope by 5.5, and optimism by 6.5 (p < 0.0001). ANCOVA models confirmed robust effects after adjusting for baseline scores and age (Δ SMD > 1). CONCLUSIONS: Virtual social interactions significantly enhance PsyCap in chemotherapy patients. However, to confidently generalize these findings and make recommendations, similar studies need to be conducted and replicated in larger, multicenter trials.