STAT+:礼来表示“三重G”药物在糖尿病研究中胜过诺和诺德的Ozempic
摘要
礼来周三表示,在一项大型糖尿病研究中,其在研药物在降血糖和减重方面比诺和诺德的Ozempic更有效,进一步提升了其药物的竞争力。在这项头对头研究中,使用礼来名为retatrutide药物最高剂量的人在80周后,一项称为A1c的血糖指标降低了2.2个百分点,而使用Ozempic的人降低了1.8个百分点。使用retatrutide最高剂量的人还减掉了20.9%的体重,考虑到糖尿病患者使用这些药物时往往不会减掉这么多体重,这是一个非常显著的幅度。与此同时,服用Ozempic的人减掉了9.4%的体重。这些结果基于仅分析那些 sta 的参与者。
English
Eli Lilly on Wednesday said that its investigational drug was more effective at lowering blood sugar and cutting weight than Novo Nordisk’s Ozempic in a large diabetes study, further boosting the competitive profile of its medicine. In the head-to-head study, people on the highest dose of Lilly’s drug, called retatrutide, saw a 2.2 percentage-point reduction in a measure of blood sugar called A1c after 80 weeks, while those on Ozempic saw a 1.8 percentage-point reduction. Those on the highest dose of retatrutide also lost 20.9% of their weight, a highly significant amount considering that people with diabetes don’t tend to lose as much weight on the drugs. Meanwhile, those taking Ozempic lost 9.4% of their weight. These results are based on analyses looking only at the participants who sta