ACOG临床实践指南：绝经相关血管运动、睡眠和情绪症状的管理。
完整摘要 · 中文译文
目的：为自然绝经和诱导绝经（在40岁或以上）相关的血管舒缩、睡眠和情绪症状的管理提供基于证据的建议。 目标人群：出生时被指定为女性性别的围绝经期和绝经后个体（即女性、跨性别男性和性别多元者），伴有与自然绝经或诱导绝经相关的血管舒缩、睡眠和情绪症状。 方法：本指南采用预先设定的方案，并联合一个写作团队制定；该团队包括一名生殖内分泌与不孕不育亚专科专家、一名绝经学会认证执业者兼生殖内分泌与不孕不育亚专科专家，以及一名妇产科专家。进入全文筛选阶段的研究由写作团队中的两名作者根据标准化的纳入和排除标准进行评估。对纳入的研究进行质量评估，并应用修正版GRADE（推荐分级的评估、制定与评价）证据到决策框架，将证据解释并转化为推荐意见。 推荐意见：本临床实践指南包括关于绝经相关血管舒缩、睡眠和情绪症状管理的药物和非药物干预措施的建议。建议按强度和证据质量分级。当因不充分或非而无法作出正式建议时，纳入未分级的良好实践要点以提供临床指导。 现有的证据。
完整摘要 · 英文原文
PURPOSE: To provide evidence-based recommendations for the management of vasomotor, sleep, and mood symptoms related to spontaneous menopause and induced menopause (at or beyond age 40 years). TARGET POPULATION: Perimenopausal and postmenopausal individuals assigned female sex at birth (ie, women, transgender men, and gender-diverse individuals) with vasomotor, sleep, and mood symptoms related to spontaneous or induced menopause. METHODS: This guideline was developed using an a priori protocol in conjunction with a writing team consisting of a subspecialist in reproductive endocrinology and infertility, a Menopause Society Certified Practitioner and subspecialist in reproductive endocrinology and infertility, and a specialist in obstetrics and gynecology. Studies that moved forward to the full-text screening stage were assessed by two authors from the writing team based on standardized inclusion and exclusion criteria. Included studies underwent quality assessment, and a modified GRADE (Grading of Recommendations Assessment, Development and Evaluation) evidence-to-decision framework was applied to interpret and translate the evidence into recommendation statements. RECOMMENDATIONS: This Clinical Practice Guideline includes recommendations on pharmacologic and nonpharmacologic interventions for the management of menopause-related vasomotor, sleep, and mood symptoms. Recommendations are classified by strength and evidence quality. Ungraded Good Practice Points are included to provide clinical guidance when a formal recommendation could not be made because of inadequate or nonexistent evidence.