科研动态期刊摘要
司美格鲁肽对射血分数保留型心力衰竭合并肥胖患者心脏结构与功能的影响：CAMEO-SEMA 试验的一项预先设定的心脏磁共振子研究
Nature Medicine · 2026-11-08
摘要
《自然·医学》，在线发表：2026年11月8日；doi:10.1038/s41591-026-04787-8 如2026年美国心脏协会科学年会上所报告，CAMEO-SEMA试验的一项心脏磁共振子研究显示，在射血分数保留型心力衰竭合并肥胖的个体中，司美格鲁肽显著改善了心脏结构与功能，包括左心房储备应变和左心室充盈动力学。
English
Effects of semaglutide on cardiac structure and function in heart failure with preserved ejection fraction and obesity: a pre-specified cardiac magnetic resonance substudy of the CAMEO-SEMA trial
Nature Medicine, Published online: 08 November 2026; doi:10.1038/s41591-026-04787-8 As presented at the 2026 AHA Scientific Sessions, a cardiac magnetic resonance substudy of the CAMEO-SEMA trial showed that semaglutide significantly improved cardiac structure and function, including left atrial reservoir strain and left ventricular filling dynamics, in individuals with heart failure with preserved ejection fraction and obesity.