温针灸对风寒湿型类风湿关节炎的临床疗效。
完整摘要 · 中文译文
目的：本研究旨在探讨温针灸治疗风寒湿痹型类风湿关节炎（RA）的临床疗效。 方法：纳入2024年1月至2024年12月期间我院收治的80例诊断为风寒湿痹型RA的患者。患者被随机分配至两组：对照组（甲氨蝶呤片）和研究组（温针灸+甲氨蝶呤片）。对两组的主要结局指标（临床症状、炎症因子水平、血清RF和ESR水平及疼痛程度）和次要结局指标（中医证候评分、不良反应总发生率及生活质量）进行比较分析。 结果：治疗两个月后，研究组相对于对照组表现出显著改善，包括晨僵持续时间缩短（P<0.01）、疼痛和肿胀关节数减少（P<0.01）、TNF-α、IL-6和CRP水平降低（P<0.01）、血清RF和ESR水平降低（P<0.01）、VAS评分降低（P<0.01）、关节畸形、关节功能受损、疼痛及畏寒的中医证候评分降低（P<0.01）、不良反应总发生率降低（P<0.05）以及WHOQOL-BREF生理、心理、社会和环境领域评分升高（P<0.01）。 结论：温针灸作为辅助疗法，在RA治疗中能有效改善症状、减轻疼痛、缓解炎症反应、提高生活质量，并具有较高的安全性。
完整摘要 · 英文原文
OBJECTIVE: The current study aimed to explore the clinical efficacy of warm acupuncture in the management of wind-cold-dampness rheumatoid arthritis (RA). METHODS: Eighty patients diagnosed with wind-cold-dampness RA and admitted to our hospital between January 2024 and December 2024 enrolled in this study. Patients were randomly allocated into two groups: a control group (methotrexate tablets) and a study group (warm acupuncture + methotrexate tablets). Comparative analyses were conducted between the two groups regarding the primary outcomes (clinical symptoms, levels of inflammatory factors, serum RF and ESR levels, and degree of pain) and secondary outcomes (TCM syndrome score, total incidence of adverse reactions and quality of life). RESULTS: Two months post-treatment, the study group demonstrated significant improvements relative to the control group, including a shorter duration of morning stiffness (P<0.01), a reduced number of painful and swollen joints (P<0.01), lower levels of TNF-α, IL-6 and CRP (P<0.01), lower serum RF and ESR levels (P<0.01), lower VAS scores (P<0.01), lower TCM syndrome scores of joint deformity, joint functional impairment, pain and fear of cold (P<0.01), lower total incidence rate of adverse reactions (P<0.05) and higher WHOQOL-BREF scores of physiology, psychology, society and environment (P<0.01). CONCLUSION: Warm acupuncture, when used as an adjunct therapy, effectively ameliorates symptoms, alleviates pain, mitigates inflammatory responses, enhances quality of life, and exhibits a high safety profile in the treatment of RA.