Post-Stroke Depression and Determinants in Ethiopia; A Systematic Review and Meta-Analysis.
完整摘要 · 中文译文
引言：卒中后抑郁是恢复和康复的重要障碍，导致严重残疾、认知和功能下降、日常生活依赖程度更高以及治疗依从性差的风险增高。此外，卒中后抑郁是全球主要死亡原因之一。卒中后抑郁的患病率因研究类型和所用筛查方法的不同而存在显著差异。然而，在世界许多地区，尤其是发展中国家，对其仍知之甚少且研究不足。为确定卒中后抑郁的关键决定因素，开展系统综述和荟萃分析至关重要，且与当前临床实践密切相关。 方法：在开展本综述时，采用了国际系统综述和荟萃分析优先报告条目清单。本综述聚焦于考察埃塞俄比亚卒中后抑郁患病率及其决定因素的研究。两位作者在PubMed、Google Scholar、Science Direct和African Journals Online Library进行了电子检索，检索时间截至2024年4月8日。数据使用Microsoft Excel提取，并导出至STATA version 11软件进行分析。研究间的异质性通过Cochran's Q检验和I2统计量进行评估。 结果：分析纳入了最终8项研究。卒中后抑郁的合并患病率为40.9%（95% CI：26.52-55.28，p < 0.001）。分析显示纳入研究间存在显著异质性（I2 = 91.1%，p < 0.001）。女性（OR 3.51，95% CI：1.87-6.58）、b 文盲（OR 2.02，95% CI：1.29-3.17）和年龄超过40岁（OR = 1.59，95% CI：1.09，2.32）是卒中后抑郁的决定因素。 结论：根据本综述，卒中后抑郁在埃塞俄比亚的患病率很高。女性、文盲和年龄超过40岁是与卒中后抑郁相关的因素。因此，应重视加强社会支持；卫生专业人员应侧重于减轻残疾/身体依赖和抑郁，因为这些是改善生活质量的关键因素。
完整摘要 · 英文原文
INTRODUCTION: Post stroke depression is a critical barrier to recovery and rehabilitation, contributing to a higher risk of severe disability, cognitive and functional decline, greater dependence on daily activities, and poor adherence to treatment. Additionally, post-stroke depression is a leading cause of death globally. The prevalence of PSD varies significantly depending on the type of study and screening methods used. However, it remains poorly understood and inadequately explored in many parts of the world, especially in developing countries. To identify the key determinants of PSD, conducting a systematic review and meta-analysis is crucial and relevant to current clinical practices. METHODS: In conducting this review, the International Preferred Reporting Items for Systematic Reviews and Meta-Analyses checklist was used. This review focused on studies examining the prevalence of post-stroke depression and its determinants in Ethiopia. Two authors conducted electronic searches in PubMed, Google Scholar, Science Direct, and African Journals Online Library, with the search period extending until April 8, 2024. Data were extracted using Microsoft Excel and exported to STATA version 11 software for analysis. Heterogeneity of studies was assessed by Cochran's Q test and I2 statistics. RESULTS: The analysis included the final eight studies. The pooled prevalence of post stroke depression was 40.9% (95% CI: 26.52-55.28, p < 0.001). The analysis revealed significant heterogeneity among the included studies (I2 = 91.1%, p < 0.001). Being female (OR 3.51, 95% CI: 1.87-6.58), being illiterate (OR 2.02, 95% CI: 1.29-3.17), and being over 40 years old (OR = 1.59, 95% CI: 1.09, 2.32) were determinants of post stroke depression. CONCLUSIONS: According to the current review, post stroke depression is highly prevalent in Ethiopia. Being female, being illiterate and being over 40 years old were factors associated with post stroke depression. Therefore, attention should be given to strengthening social support; health professionals should focus on reducing disability/physical dependency and depression, as these are vital factors for improving quality of life.
摘要 待译
INTRODUCTION: Post stroke depression is a critical barrier to recovery and rehabilitation, contributing to a higher risk of severe disability, cognitive and functional decline, greater dependence on daily activities, and poor adherence to treatment. Additionally, post-stroke depression is a leading cause of death globally. The prevalence of PSD varies significantly depending on the type of study and screening methods used. However, it remains poorly understood and inadequately explored in many parts of the world, especially in developing countries.…