The impact of rising global temperatures on neurological diseases.
完整摘要 · 中文译文
背景：主要由人为活动驱动的气候变化是21世纪的一项决定性挑战。尽管其一般健康影响已有充分记录，但全球变暖对神经系统疾病的具体影响数十年来一直未得到足够重视。 目的：通过系统综述评估全球气温上升与多种神经系统疾病加重或发病之间的关联。 方法：在PubMed/MEDLINE和SciELO数据库中对2011年至2026年间发表的研究进行了系统检索。按照严格的纳入标准，最终选取13篇同行评审文章进行定性综合。 结果：证据显示，气温上升与癫痫、卒中、多发性硬化（MS）以及阿尔茨海默病和帕金森病等神经退行性疾病的病情恶化日益相关。具体而言，热暴露与更高的住院率和急性症状加重相关，如MS中的乌托夫现象（Uhthoff's phenomenon）和帕金森病中的自主神经体温调节衰竭。尽管存在一些地理和方法学上的差异，尤其是在卒中和癫痫发作频率方面，但总体趋势表明神经系统对热应激的脆弱性增加。 结论：尽管研究正在不断扩展，神经系统疾病仍是气候危机中研究不足的前沿领域。有针对性的科学研究和有力的公共卫生策略对于减轻气候变暖带来的新兴神经系统风险至关重要。 净。
完整摘要 · 英文原文
BACKGROUND: Climate change, driven predominantly by anthropogenic actions, represents a defining challenge of the 21st century. While its general health implications are well documented, the specific impact of global warming on neurological diseases has remained underemphasized for decades. OBJECTIVE: To evaluate the association between rising global temperatures and the exacerbation or incidence of various neurological conditions through a systematic review. METHODS: A systematic search was conducted in the PubMed/MEDLINE and SciELO databases for studies published between 2011 and 2026. Following strict eligibility criteria, 13 peer-reviewed articles were selected for qualitative synthesis. RESULTS: The evidence reveals that rising temperatures are increasingly linked to the worsening of conditions such as epilepsy, stroke, multiple sclerosis (MS), and neurodegenerative disorders like Alzheimer's and Parkinson's diseases. Specifically, heat exposure is associated with higher hospitalization rates and acute symptom exacerbation, such as Uhthoff's phenomenon in MS and autonomic thermoregulatory failure in Parkinson's. Although some geographic and methodological discrepancies exist, particularly regarding stroke and seizure frequency, the overall trend indicates increased neurological vulnerability to thermal stress. CONCLUSION: While research is expanding, neurological diseases remain an understudied frontier of the climate crisis. Targeted scientific investigation and robust public health strategies are imperative to mitigate the emerging neurological risks of a warming planet.
摘要 待译
BACKGROUND: Climate change, driven predominantly by anthropogenic actions, represents a defining challenge of the 21st century. While its general health implications are well documented, the specific impact of global warming on neurological diseases has remained underemphasized for decades. OBJECTIVE: To evaluate the association between rising global temperatures and the exacerbation or incidence of various neurological conditions through a systematic review. METHODS: A systematic search was conducted in the PubMed/MEDLINE and SciELO databases for studies published between 2011 and 2026.…