[Seminar] Eating disorders
完整摘要 · 中文译文
进食和喂养障碍是处于心身界面的严重精神障碍，通常对患者本人、其家人和支持者以及更广泛的社会造成极高的负担。在神经性厌食症中，高急性医学风险与患者对治疗的矛盾心理可能形成具有挑战性的组合，从而阻碍治疗参与。进食障碍的一线治疗主要为心理治疗，药物起辅助作用。新的生物学和技术干预手段才刚刚缓慢出现。与其他精神障碍相比，对这些障碍的研究严重资金不足。关于其病因、维持机制和治疗仍存在许多不确定性。争议主要涉及对最严重和病程最长的患者的治疗和照护。知识的进步最有可能来自结合多模式评估的纵向研究、利用大数据以形成更好的机制性理解，以及更多使用灵活的试验设计以开发更个性化和更精确的干预措施。
完整摘要 · 英文原文
The eating and feeding disorders are serious psychiatric disorders at the mind-body interface, often with an exceptionally high burden for affected individuals, their families and supporters, and wider society. In anorexia nervosa, high acute medical risk and patients' ambivalence about treatment can make a challenging combination that can impede engagement. First-line treatments for eating disorders are mainly psychological, with medications playing an adjunctive role. Novel biological and technology-based interventions are only slowly emerging. Compared with other psychiatric disorders, research into these disorders is seriously underfunded. Many uncertainties regarding their aetiology, maintenance, and treatment remain. Controversies mainly concern the treatment and care of those with the most severe and longstanding forms of illness. Advances in knowledge are most likely to arise from longitudinal studies combining multimodal assessments, using big data to develop better mechanistic understanding, and greater use of flexible trial designs to allow development of more personalised and precise interventions.
摘要 待译
The eating and feeding disorders are serious psychiatric disorders at the mind–body interface, often with an exceptionally high burden for affected individuals, their families and supporters, and wider society. In anorexia nervosa, high acute medical risk and patients’ ambivalence about treatment can make a challenging combination that can impede engagement. First-line treatments for eating disorders are mainly psychological, with medications playing an adjunctive role. Novel biological and technology-based interventions are only slowly emerging.