Effectiveness of a Structured Post-Platelet Rich Plasma Rehabilitation Approach on Pain and Function in Subacromial Pain Syndrome: A Randomized Controlled Trial.
完整摘要 · 中文译文
背景与目的：肩峰下疼痛综合征（SAPS）会导致疼痛和功能受限。富血小板血浆（PRP）正越来越多地被用作辅助治疗。PRP后的最佳康复方案尚不明确。本研究探讨了PRP后结构化康复方案对疼痛和功能的有效性。 方法：60名SAPS参与者被随机分为两组；54人完成了研究并纳入最终的符合方案分析（每组27人）。在21天期间，研究组在标准常规物理治疗之外接受PRP后结构化康复方案，而对照组仅接受标准常规物理治疗。评估了关节活动度、肌肉力量和姿势。此外，结局指标包括简化McGill疼痛问卷（SF-MPQ）、视觉模拟量表（VAS）、臂、肩和手功能障碍问卷（DASH）、手和颈/肩/臂功能损害测试（FIT-HaNSA）以及Constant-Murley肩关节评分，这些均用于评估目的。 结果：两组的Corbin姿势量表评分均下降（p < 0.05）。研究组的疼痛减轻程度更大（VAS：从9.00 ± 0.67降至2.92 ± 1.14，对照组从9.11 ± 0.64降至7.96 ± 0.75；SF-MPQ：从27.07 ± 4.41降至10.07 ± 3.33，对照组从21.33 ± 2.46降至19.37 ± 2.35；p < 0.001）。研究组在Constant-Murley、DASH和FIT-HaNSA评分、肩部肌肉力量以及主动和被动关节活动度方面的改善显著更大（p < 0.001）。 讨论： 在标准常规物理治疗的基础上增加结构化的富血小板血浆（PRP）注射后康复方案，与单独使用标准常规物理治疗相比，可能为肩峰下疼痛综合征（SAPS）患者在疼痛、肌肉力量、关节活动度和肩关节功能方面提供额外的短期改善。然而，未进行长期随访。因此，所观察到的改善的可持续性仍不明确。未来研究应探讨结构化PRP注射后康复方案的长期效果。 试验注册：ClinicalTrials.gov标识符：NCT07410208；于2026年1月21日注册。
完整摘要 · 英文原文
BACKGROUND AND PURPOSE: Subacromial pain syndrome (SAPS) causes pain and functional limitation. Platelet-Rich Plasma (PRP) is increasingly used as a supportive treatment. Optimal rehabilitation after PRP is unclear. This study investigated the effectiveness of a structured post-PRP rehabilitation approach on pain and function. METHODS: Sixty participants with SAPS were randomized to two groups; 54 completed the study and were included in the final per-protocol analysis (27 per group). During a 21-day period, the study group received a structured post-PRP rehabilitation approach in addition to standard conventional physiotherapy, while the control group received standard conventional physiotherapy alone. Range of motion, muscle strength, and posture were evaluated. In addition, outcome measures included the Short-Form McGill Pain Questionnaire (SF-MPQ), Visual Analogue Scale (VAS), Disabilities of the Arm, Shoulder and Hand Questionnaire (DASH), Functional Impairment Test-Hand and Neck/Shoulder/Arm (FIT-HaNSA) and Constant-Murley Shoulder Score, which were administered for assessment purposes. RESULTS: Corbin Posture Scale scores decreased in both groups (p < 0.05). Pain reduction was greater in the study group (VAS: from 9.00 ± 0.67 to 2.92 ± 1.14 versus from 9.11 ± 0.64 to 7.96 ± 0.75; SF-MPQ: from 27.07 ± 4.41 to 10.07 ± 3.33 versus from 21.33 ± 2.46 to 19.37 ± 2.35; p < 0.001). Improvements in Constant-Murley, DASH, and FIT-HaNSA scores, shoulder muscle strength, and active and passive range of motion were significantly greater in the study group (p < 0.001). DISCUSSION: Adding a structured post-PRP rehabilitation approach to standard conventional physiotherapy may provide additional short-term improvements in pain, muscle strength, range of motion, and shoulder function compared with standard conventional physiotherapy alone in individuals with SAPS. However, long-term follow-up was not conducted. Therefore, the sustainability of the observed improvements remains unclear. Future studies should investigate the long-term effects of structured post-PRP rehabilitation approaches. TRIAL REGISTRATION: ClinicalTrials.gov identifier: NCT07410208; registered on January 21, 2026.
摘要 待译
BACKGROUND AND PURPOSE: Subacromial pain syndrome (SAPS) causes pain and functional limitation. Platelet-Rich Plasma (PRP) is increasingly used as a supportive treatment. Optimal rehabilitation after PRP is unclear. This study investigated the effectiveness of a structured post-PRP rehabilitation approach on pain and function. METHODS: Sixty participants with SAPS were randomized to two groups; 54 completed the study and were included in the final per-protocol analysis (27 per group).…