Effects of complementary therapies on physiological and psychological outcomes in chronic obstructive pulmonary disease patients: A systematic review and meta-analysis of randomized controlled trials.
完整摘要 · 中文译文
背景：肺康复（PR）是改善慢性阻塞性肺疾病（COPD）患者呼吸功能和症状的基石干预措施。然而，关于补充疗法（CTs），如瑜伽、太极/气功、音乐疗法、认知行为疗法（CBT）、放松技术和水中运动等效果的证据仍然有限。 方法：在Embase、Scopus、PubMed和MEDLINE（Ovid）中系统检索了涉及COPD患者的随机对照试验（RCTs）。研究筛选遵循PRISMA指南。连续结局采用随机效应模型以均数差（MDs）进行合并。 结果：共纳入36项RCTs，涉及3148名参与者。与常规护理相比，不同补充疗法对运动能力的影响各异，改善主要见于基于运动的干预方式（6分钟步行距离[6MWD]；MD = 58.73 m）、肺功能（FEV1占预计值百分比；MD = 4.65）、呼吸困难（改良Borg量表；MD = -0.79；CRQ呼吸困难维度；MD = 1.03）、症状负担（COPD评估测试；MD = -3.36）以及健康相关生活质量（SGRQ总分；MD = -8.40）。焦虑和抑郁（HADS-A和HADS-D）也有所减轻（MD分别为-1.70和-1.02）。与肺康复相比，补充疗法在6MWD（MD = 8.17）和HADS-D（MD = -0.74）方面显示出更大的改善。 结论：补充疗法可能改善COPD患者的生理和心理结局，并可作为一种常规肺康复的辅助策略。仍需进一步研究以ide 确定最佳治疗方式和患者特异性反应。
完整摘要 · 英文原文
BACKGROUND: Pulmonary rehabilitation (PR) is the cornerstone intervention for improving respiratory function and symptoms in patients with chronic obstructive pulmonary disease (COPD). However, evidence on the effects of complementary therapies (CTs), such as yoga, tai chi/qigong, music therapy, cognitive behavioral therapy (CBT), relaxation techniques, and water-based exercise, remains limited. METHODS: Randomized controlled trials (RCTs) involving patients with COPD were systematically searched in Embase, Scopus, PubMed, and MEDLINE (Ovid). Study selection followed PRISMA guidelines. Continuous outcomes were pooled as mean differences (MDs) using random-effects models. RESULTS: Thirty-six RCTs involving 3148 participants were included. Compared with usual care, effects on exercise capacity varied across different CTs, with improvements observed primarily in exercise-based approaches (6-min walk distance [6MWD]; MD = 58.73 m), pulmonary function (FEV1% predicted; MD = 4.65), dyspnea (modified Borg scale; MD = -0.79; CRQ dyspnea; MD = 1.03), symptom burden (COPD Assessment Test; MD = -3.36), and health-related quality of life (SGRQ total score; MD = -8.40). Anxiety and depression (HADS-A and HADS-D) were also reduced (MD = -1.70 and -1.02, respectively). Compared with PR, CTs showed greater improvements in 6MWD (MD = 8.17) and HADS-D (MD = -0.74). CONCLUSION: Complementary therapies may improve both physiological and psychological outcomes in patients with COPD and may serve as adjunctive strategies to conventional pulmonary rehabilitation. Further research is needed to identify optimal modalities and patient-specific responses.
摘要 待译
BACKGROUND: Pulmonary rehabilitation (PR) is the cornerstone intervention for improving respiratory function and symptoms in patients with chronic obstructive pulmonary disease (COPD). However, evidence on the effects of complementary therapies (CTs), such as yoga, tai chi/qigong, music therapy, cognitive behavioral therapy (CBT), relaxation techniques, and water-based exercise, remains limited. METHODS: Randomized controlled trials (RCTs) involving patients with COPD were systematically searched in Embase, Scopus, PubMed, and MEDLINE (Ovid). Study selection followed PRISMA guidelines.…