科研动态期刊摘要
围手术期艾万妥单抗联合或不联合化疗治疗可切除非小细胞肺癌：一项2期试验
Nature Medicine · 2026-11-05
摘要
《自然·医学》，在线发表：2026年11月4日；doi:10.1038/s41591-026-04745-4 在一项非随机2期试验中，可切除非小细胞肺癌患者接受围手术期艾万妥单抗单药或联合化疗治疗，两个队列均获得令人鼓舞的病理缓解率，且新辅助治疗期间持续的循环肿瘤DNA阴性可能预测缓解。
English
Perioperative ivonescimab with or without chemotherapy in resectable non-small cell lung cancer: a phase 2 trial
Nature Medicine, Published online: 04 November 2026; doi:10.1038/s41591-026-04745-4 In a nonrandomized phase 2 trial, patients with resectable non-small cell lung cancer received perioperative ivonescimab as monotherapy or with chemotherapy, leading to encouraging pathological response rates in both cohorts, and sustained circulating tumor DNA negativity throughout neoadjuvant therapy may be predictive of response.