粘连性肩关节囊炎干预措施:随机对照试验的系统评价与网络荟萃分析
摘要
摘要目的 比较粘连性肩关节囊炎治疗干预措施的获益与危害。设计 随机对照试验的系统评价与网络荟萃分析。数据来源 检索Medline、Cochrane Library、Embase、Web of Science和Scopus,检索时间自建库至2025年5月1日,并于2025年11月更新。研究选择标准 纳入成人为粘连性肩关节囊炎患者的随机对照试验,比较积极治疗与另一种干预、安慰剂或常规护理。主要结局指标 疼痛、功能、关节活动度和不良事件。结果 共纳入189项随机对照试验,涉及12 988名参与者和59种干预措施。对主要结局有贡献的大多数试验存在高偏倚风险(p为71%
English
AbstractObjectiveTo compare the benefits and harms of therapeutic interventions for adhesive capsulitis.DesignSystematic review and network meta-analysis of randomised controlled trials.Data sourcesMedline, Cochrane Library, Embase, Web of Science, and Scopus were searched from inception to 1 May 2025, with an update in November 2025.Eligibility criteria for selecting studiesRandomised controlled trials enrolling adults with adhesive capsulitis, comparing active treatment with another intervention, placebo, or usual care.Main outcome measuresPain, function, range of motion, and adverse events.ResultsA total of 189 randomised controlled trials involving 12 988 participants and 59 interventions were included. Most trials contributing to principal outcomes were at high risk of bias (71% for p