接受腺样体扁桃体切除术的儿童使用喉罩通气与气管插管通气的围术期呼吸不良事件：多中心、随机对照试验
摘要
摘要目的 评估喉罩气道（LMA）通气与气管插管（ETT）通气相比对接受腺样体扁桃体切除术儿童围术期呼吸不良事件（PRAEs）的影响。设计 多中心、随机、平行组试验。地点 中国四家三级医院，2023-24年。参与者 400名年龄≥2岁且<7岁、拟在全身麻醉下接受腺样体扁桃体切除术的儿童。干预 参与者按1：1随机分配，在腺样体扁桃体切除术期间接受喉罩气道通气（n=200）或气管插管通气（n=200）。主要结局指标 主要结局为发生任何围术期呼吸不良事件（PRAE）的参与者比例：喉痉挛、支气管痉挛、血氧饱和度下降、气道梗阻
English
AbstractObjectiveTo assess the effect of ventilation with a laryngeal mask airway (LMA) compared with endotracheal tube (ETT) on perioperative respiratory adverse events (PRAEs) in children undergoing adenotonsillectomy.DesignMulticentre, randomised, parallel group trial.SettingFour tertiary hospitals in China, 2023-24.Participants400 children aged ≥2 years and <7 years who were scheduled for adenotonsillectomy under general anaesthesia.InterventionsParticipants were randomised 1:1 to receive ventilation with a laryngeal mask airway (n=200) or an endotracheal tube (n=200) during adenotonsillectomy.Main outcome measureThe primary outcome was the proportion of participants who developed any perioperative respiratory adverse event (PRAE): laryngospasm, bronchospasm, desaturation, airway obstr