不同身心锻炼对稳定期慢性阻塞性肺疾病成人肺功能、运动能力和生活质量影响的比较:一项贝叶斯网络Meta分析。
完整摘要 · 中文译文
慢性阻塞性肺疾病(COPD)是全球发病率和死亡率的主要原因之一。本综述采用贝叶斯网络荟萃分析(NMA)评估了不同身心运动(MBE)对稳定期COPD成人肺功能(LF)、运动能力(EC)和生活质量(QoL)的影响。检索了截至2026年4月21日的八个英文和中文数据库。纳入比较八段锦(BDJ)、易筋经(YJJ)、瑜伽、六字诀(LZJ)、太极拳(TC)和五禽戏(WQX)与常规护理(UC)的随机对照试验。结局包括FEV1、FEV1%pred、FEV1/FVC、FVC、6分钟步行距离(6MWD)、圣乔治呼吸问卷(SGRQ)和COPD评估测试(CAT)。使用R进行贝叶斯NMA。共纳入111项随机对照试验,涉及9,240名参与者。大多数试验比较了单一MBE与UC,不同MBE之间的直接头对头比较有限。不同MBE方式在LF、EC和QoL结局方面显示出潜在获益,尽管效果因结局而异。根据累积排序曲线下面积(SUCRA)排序,瑜伽在FEV1(均数差[MD]=0.48,95%可信区间[CrI]:0.11,0.85)和FVC(MD=0.46,95%CrI:0.09,0.83)方面排名最高,而WQX在FEV1/FVC(MD=8.38,95%CrI:4.59,12.3)和FEV1%pred(MD=10.2,95%CrI:5.25,15.35)方面排名最高。WQX在6MWD方面排名最高,而瑜伽、TC和YJJ在某些QoL相关结局方面显示出有利的排序。然而,这些发现应谨慎解释,因为一些干预措施为 这一结论仅由数量相对较少的试验支持,这些试验的证据确定性不一且存在潜在偏倚风险,且纳入的试验主要在中国开展。冥想类身心锻炼(MBEs)可能改善稳定期COPD成人的肺功能(LF)、运动能力(EC)和生活质量(QoL)。不同的MBEs对特定结局显示出潜在益处。然而,由于直接证据有限、可用试验数量不等以及证据确定性存在差异,比较效应仍不确定。需要进一步开展高质量的头对头随机对照试验(RCTs)来证实这些发现。
完整摘要 · 英文原文
Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. This review evaluated the effects of different mind-body exercises (MBEs) on lung function (LF), exercise capacity (EC), and quality of life (QoL) in adults with stable COPD using Bayesian network meta-analysis (NMA). Eight English and Chinese databases were searched through April 21, 2026. Randomized controlled trials comparing Ba Duan Jin (BDJ), Yi Jin Jing (YJJ), yoga, Liu Zi Jue (LZJ), Tai Chi (TC), and Wu Qin Xi (WQX) with usual care (UC) were included. Outcomes included FEV1, FEV1%pred, FEV1/FVC, FVC, 6-minute walk distance (6MWD), St. George's Respiratory Questionnaire (SGRQ), and COPD Assessment Test (CAT). Bayesian NMA was conducted using R. A total of 111 RCTs involving 9,240 participants were included. Most trials compared individual MBEs with UC, with limited direct head-to-head comparisons among different MBEs. Different MBE modalities showed potential benefits across LF, EC, and QoL outcomes, although effects varied by outcome. According to the surface under the cumulative ranking curve (SUCRA) ranking, Yoga ranked highest for FEV1 (mean difference [MD] = 0.48, 95% credible interval [CrI]: 0.11, 0.85) and FVC (MD = 0.46, 95% CrI: 0.09, 0.83), whereas WQX ranked highest for FEV1/FVC (MD = 8.38, 95% CrI: 4.59, 12.3) and FEV1%pred (MD = 10.2, 95% CrI: 5.25, 15.35). WQX ranked highest for 6MWD, whereas Yoga, TC, and YJJ showed favorable rankings for some QoL-related outcomes. However, these findings should be interpreted cautiously because some interventions were supported by a relatively small number of trials with varying certainty of evidence and potential risk of bias, and the included trials were predominantly conducted in China. MBEs may improve LF, EC, and QoL in adults with stable COPD. Different MBEs showed potential benefits for specific outcomes. However, comparative effects remain uncertain due to limited direct evidence, unequal numbers of available trials, and variability in evidence certainty. Further high-quality head-to-head RCTs are needed to confirm these findings.