伊朗学龄前和学龄儿童肠道寄生虫的流行情况：一项系统综述与荟萃分析。
完整摘要 · 中文译文
背景：肠道寄生虫感染（IPIs）是低中等收入国家儿童面临的重大公共卫生挑战，与营养不良、发育迟缓和认知缺陷相关。本荟萃分析估计了伊朗学龄前和学龄儿童IPIs的患病率，并确定了相关因素。 方法：在五个国际文献数据库（Scopus、PubMed、Web of Science、Embase和Google Scholar）中进行了系统性文献检索，以识别2000年1月至2025年5月期间发表的文章。研究方案符合流行病学观察性研究荟萃分析（MOOSE）报告指南。随后，36项研究符合纳入标准并被纳入本荟萃分析。这些研究总计涵盖48，930名个体的总样本量，其中包括3，595名确诊感染的伊朗学龄儿童。 结果：IPIs总患病率为0.081（95% CI 0.058-0.113）。在原虫中，患病率最高的是蓝氏贾第鞭毛虫（0.080，95% CI：0.056-0.112），在蠕虫中患病率最高的是蛲虫（0.031，95% CI：0.020-0.048）。学龄前儿童感染率最高（0.130，95% CI：0.070-0.210）。 结论：为减少伊朗儿童的肠道寄生虫感染，建议对学龄前和学龄儿童进行定期筛查，尤其是在患病率最高的潮湿地区。必须评估和加强学校卫生系统，包括适当的卫生 洗手设施、手卫生基础设施和卫生教育。此外，以学校为基础的驱虫项目、减少游乐场土壤污染等环境措施，以及劝阻食土的社区健康宣传活动，对于阻断传播循环和预防长期并发症至关重要。
完整摘要 · 英文原文
BACKGROUND: Intestinal parasitic infections (IPIs) are a major public health challenge for children in low- and middle-income countries, linked to malnutrition, stunting, and cognitive deficits. This meta-analysis estimated IPIs prevalence in Iranian preschool and school-aged children and identified associated factors. METHODS: A systematic literature search was performed across five international bibliographic databases (Scopus, PubMed, Web of Science, Embase, and Google Scholar) to identify articles published between January 2000 and May 2025. The study protocol was in accordance with the reporting guidelines for the Meta-analysis of Observational Studies in Epidemiology (MOOSE). Subsequently, 36 studies met the eligibility criteria and were incorporated into the present meta-analysis. These studies in total accounted for a total sample size of 48,930 individuals, including 3,595 school-aged children in Iran with confirmed infections. RESULTS: Overall IPIs prevalence was 0.081 (95% CI 0.058-0.113). Among protozoa, the highest prevalence was related to Giardia lamblia (0.080, 95% CI: 0.056-0.112) and the most prevalent helminths, was Enterobius vermicularis (0.031, 95% CI: 0.020-0.048). Preschool children showed the highest rate of infection (0.130, 95% CI: 0.070-0.210). CONCLUSION: To reduce intestinal parasitic infections in Iranian children, regular and periodic screening of pre-school and school-aged children is recommended, particularly in humid regions where prevalence is highest. Health systems within schools must be evaluated and strengthened, including proper sanitation facilities, handwashing infrastructure, and hygiene education. Additionally, school-based deworming programs, environmental measures such as reducing soil contamination in playgrounds, and community health campaigns discouraging geophagy are essential to interrupt transmission cycles and prevent long-term complications.