💉 Tetanus Prophylaxis (Wound Management)
UseUse during wound care to decide vaccine and TIG, accounting for contaminated wounds and immunocompromise.
SourceLiang JL, et al. Prevention of Pertussis, Tetanus, and Diphtheria with Vaccines (ACIP recommendatio…
This-shift next steps
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Methodology · worked example, guidelines & full notes
A clean minor wound never warrants TIG, whereas a contaminated wound in an under-immunized or immunocompromised patient does. (original synthesis · not guideline verbatim)
When to use
Use during wound care to decide vaccine and TIG, accounting for contaminated wounds and immunocompromise.
How it works
Clean minor wound → vaccine only if history unknown/incomplete or > 10 yr; never TIG. Contaminated/larger wound → vaccine + TIG if history unknown/incomplete, vaccine booster if > 5 yr. HIV/severe immunodeficiency + dirty wound → TIG regardless.
Key points
- A clean minor wound never warrants TIG, whereas a contaminated wound in an under-immunized or immunocompromised patient does. (original synthesis · not guideline verbatim)
- TIG neutralizes only free toxin, so thorough wound debridement remains essential.
- Antibiotics do not substitute for immunoprophylaxis, and the primary series should be completed.
References
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Wound type | Clean minor wound |
|---|---|
| Tetanus immunization history | ≥ 3 doses and < 5 yr since last |
| HIV or severe immunodeficiency | No |
→DispositionNo vaccine needed
- Vaccine：No tetanus vaccine needed
- TIG：No TIG needed (a clean minor wound never needs TIG)
- Wound care：Thorough debridement, irrigation, removal of devitalized tissue and foreign bodies; TIG only neutralizes free toxin, not toxin already bound to nerve endings, so give early when indicated
| Wound type | Clean minor wound |
|---|---|
| Tetanus immunization history | Unknown or < 3 doses |
| HIV or severe immunodeficiency | No |
→DispositionGive vaccine
- Vaccine：Give a tetanus-toxoid-containing vaccine (Td/Tdap, [pending update]; prefer Tdap if never given Tdap, Tdap in pregnancy)
- TIG：No TIG needed (a clean minor wound never needs TIG)
- Wound care：Thorough debridement, irrigation, removal of devitalized tissue and foreign bodies; TIG only neutralizes free toxin, not toxin already bound to nerve endings, so give early when indicated
Verification & sources · governance
FAQ
Frequently asked questions
- What are the limits and cautions when using Tetanus Prophylaxis (Wound Management)?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- Does Tetanus Prophylaxis (Wound Management) upload patient data? Where is it calculated?
- Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
- How is Tetanus Prophylaxis (Wound Management) calculated in practice? Can you show a worked example?
- Inputs: Wound type Clean minor wound, Tetanus immunization history ≥ 3 doses and < 5 yr since last, HIV or severe immunodeficiency No → Result: Disposition No vaccine needed（Vaccine: No tetanus vaccine needed, TIG: No TIG needed (a clean minor wound never needs TIG), Wound care: Thorough debridement, irrigation, removal of devitalized tissue and foreign bodies; TIG only neutralizes free toxin, not toxin already bound to nerve endings, so give early when indicated） Inputs: Wound type Clean minor wound, Tetanus immunization history Unknown or < 3 doses, HIV or severe immunodeficiency No → Result: Disposition Give vaccine（Vaccine: Give a tetanus-toxoid-containing vaccine (Td/Tdap, [pending update]; prefer Tdap if never given Tdap, Tdap in pregnancy), TIG: No TIG needed (a clean minor wound never needs TIG), Wound care: Thorough debridement, irrigation, removal of devitalized tissue and foreign bodies; TIG only neutralizes free toxin, not toxin already bound to nerve endings, so give early when indicated）