Bedside steps

1. 1
   Vancomycin

   Empiric vancomycin loading dose, maintenance dose and interval by weight and creatinine clearance (AUC-guided; requires…

   Calculate here · Vancomycin ▾Full details →
2. 2
   Abx spectrum

   Overview of the coverage (spectrum) of common antibiotic classes; empiric choice must factor in local susceptibility (e…

   Calculate here · Abx spectrum ▾Full details →
3. 3
   Abx renal adjust

   Adjustment/avoidance points and key safety notes for common antibiotics by renal function (CrCl); includes a 'generally…

   Calculate here · Abx renal adjust ▾Full details →
4. 4
   PK/PD dosingAlternate branch

   PK/PD targets and optimised dosing strategies for time-dependent / concentration-dependent / AUC-type antibiotics (exte…

   Calculate here · PK/PD dosing ▾Full details →
5. 5
   CAP triageAlternate branch

   Uses CURB-65 and severe-CAP criteria to give outpatient/inpatient/ICU triage and the empiric antimicrobial direction.

   Calculate here · CAP triage ▾Full details →

[Antimicrobials · bedside workflow]
Vancomycin：not calculated
Abx spectrum：not calculated
Abx renal adjust：not calculated
PK/PD dosing：not calculated
CAP triage：not calculated
Guideline：Empiric antimicrobials & PK/PD (see tool pages for exact version notes)
Reviewed：2026-09-05
For licensed clinicians only. Local calculation; does not replace clinical judgment or individualized shared decision-making. Integrate guideline version, patient preference, and bleed–thrombosis trade-offs.

For licensed clinicians only. Local calculation; does not replace clinical judgment or individualized shared decision-making. Integrate guideline version, patient preference, and bleed–thrombosis trade-offs.