🎗️ GTN WHO/FIGO Prognostic Score
UseDecide between single-agent and combination chemotherapy in GTN.
Loading calculator…
SourceFIGO Oncology Committee. FIGO staging for gestational trophoblastic neoplasia 2000.
Runs locally in your browser (no PHI uploaded). For licensed clinicians — not a substitute for clinical judgement.
Stored on this device for revisit reminders
This-shift next steps
After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.
Scene next step
📋gyn oncoOpen scene pack →Related scores
Matching pathway
🧭cervical_ca_mriOpen pathway →Score + version; reference only — not a substitute for care · no HIS write
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Methodology · worked example, guidelines & full notes
Clinical takeaway
Low risk → single-agent (methotrexate/actinomycin D).
When to use
Decide between single-agent and combination chemotherapy in GTN.
How it works
Sum 8 factors (age, antecedent pregnancy, interval, hCG, tumor size, metastatic site, number of metastases, prior failed chemo). ≤ 6 low risk, ≥ 7 high risk.
Key points
- Low risk → single-agent (methotrexate/actinomycin D).
- High risk → combination chemotherapy (e.g. EMA-CO).
- Expressed with the FIGO anatomic stage; not for PSTT/ETT.
References
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Age | < 40 y (0) |
|---|---|
| Antecedent pregnancy | Abortion (1) |
| Interval from antecedent pregnancy (months) | 4–6 (1) |
| Pretreatment serum hCG (IU/L) | 10³–10⁴ (1) |
| Largest tumor (incl. uterus) | 3–4 cm (1) |
| Site of metastases | Spleen/kidney (1) |
| Number of metastases | 1–4 (1) |
| Prior failed chemotherapy | Single agent (2) |
→FIGO score8
- Prognostic score：8 → High risk (≥ 7)
- Treatment：High-risk GTN: combination chemotherapy (e.g. EMA-CO), salvage and multidisciplinary care as needed; individualized treatment for brain/liver metastases
- Note：Expressed with the FIGO anatomic stage (e.g. III:5); does not apply to PSTT or epithelioid trophoblastic tumor
| Age | < 40 y (0) |
|---|---|
| Antecedent pregnancy | Hydatidiform mole (0) |
| Interval from antecedent pregnancy (months) | < 4 (0) |
| Pretreatment serum hCG (IU/L) | < 10³ (0) |
| Largest tumor (incl. uterus) | < 3 cm (0) |
| Site of metastases | Lung (0) |
| Number of metastases | 0 (0) |
| Prior failed chemotherapy | None (0) |
→FIGO score0
- Prognostic score：0 → Low risk (≤ 6)
- Treatment：Low-risk GTN: single-agent chemotherapy (methotrexate or actinomycin D); switch agent or escalate if resistant
- Note：Expressed with the FIGO anatomic stage (e.g. III:5); does not apply to PSTT or epithelioid trophoblastic tumor
Verification & sources · governance
FAQ
Frequently asked questions
- What are the limits and cautions when using GTN WHO/FIGO Prognostic Score?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- Does GTN WHO/FIGO Prognostic Score upload patient data? Where is it calculated?
- Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
- How is GTN WHO/FIGO Prognostic Score calculated in practice? Can you show a worked example?
- Inputs: Age < 40 y (0), Antecedent pregnancy Abortion (1), Interval from antecedent pregnancy (months) 4–6 (1), Pretreatment serum hCG (IU/L) 10³–10⁴ (1), Largest tumor (incl. uterus) 3–4 cm (1), Site of metastases Spleen/kidney (1), Number of metastases 1–4 (1), Prior failed chemotherapy Single agent (2) → Result: FIGO score 8（Prognostic score: 8 → High risk (≥ 7), Treatment: High-risk GTN: combination chemotherapy (e.g. EMA-CO), salvage and multidisciplinary care as needed; individualized treatment for brain/liver metastases, Note: Expressed with the FIGO anatomic stage (e.g. III:5); does not apply to PSTT or epithelioid trophoblastic tumor） Inputs: Age < 40 y (0), Antecedent pregnancy Hydatidiform mole (0), Interval from antecedent pregnancy (months) < 4 (0), Pretreatment serum hCG (IU/L) < 10³ (0), Largest tumor (incl. uterus) < 3 cm (0), Site of metastases Lung (0), Number of metastases 0 (0), Prior failed chemotherapy None (0) → Result: FIGO score 0（Prognostic score: 0 → Low risk (≤ 6), Treatment: Low-risk GTN: single-agent chemotherapy (methotrexate or actinomycin D); switch agent or escalate if resistant, Note: Expressed with the FIGO anatomic stage (e.g. III:5); does not apply to PSTT or epithelioid trophoblastic tumor）