🧬 Khorana Score (Chemotherapy VTE Risk)
UseStratify VTE risk in ambulatory patients on chemotherapy.
SourceKhorana AA, et al. Blood 2008
This-shift next steps
After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.
Paste the link in Slack, Teams, X, or LinkedIn — the preview image comes from this page’s Open Graph card.
Methodology · worked example, guidelines & full notes
Validation VTE rates: 0.3% / 2% / 6.7%.
When to use
Stratify VTE risk in ambulatory patients on chemotherapy.
How it works
Cancer site (2/1/0) + platelets ≥ 350 (1) + Hb < 10/ESA (1) + WBC > 11 (1) + BMI ≥ 35 (1). ≥ 2 = high risk.
Key points
- Validation VTE rates: 0.3% / 2% / 6.7%.
- Assesses VTE risk only, not bleeding risk.
- Validated for ambulatory patients starting chemotherapy.
References
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Cancer site | High risk: lung, lymphoma, gynae, bladder, testicular (1) |
|---|---|
| Platelets ≥ 350 ×10⁹/L | No |
| Hb < 10 g/dL or using ESA | No |
| WBC > 11 ×10⁹/L | No |
| BMI ≥ 35 kg/m² | No |
→Khorana1
- Risk：Intermediate risk
| Cancer site | Other (0) |
|---|---|
| Platelets ≥ 350 ×10⁹/L | No |
| Hb < 10 g/dL or using ESA | No |
| WBC > 11 ×10⁹/L | No |
| BMI ≥ 35 kg/m² | No |
→Khorana0
- Risk：Low risk
Verification & sources · governance
FAQ
Frequently asked questions
- What are the limits and cautions when using Khorana Score (Chemotherapy VTE Risk)?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- Does Khorana Score (Chemotherapy VTE Risk) upload patient data? Where is it calculated?
- Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
- How is Khorana Score (Chemotherapy VTE Risk) calculated in practice? Can you show a worked example?
- Inputs: Cancer site High risk: lung, lymphoma, gynae, bladder, testicular (1), Platelets ≥ 350 ×10⁹/L No, Hb < 10 g/dL or using ESA No, WBC > 11 ×10⁹/L No, BMI ≥ 35 kg/m² No → Result: Khorana 1（Risk: Intermediate risk） Inputs: Cancer site Other (0), Platelets ≥ 350 ×10⁹/L No, Hb < 10 g/dL or using ESA No, WBC > 11 ×10⁹/L No, BMI ≥ 35 kg/m² No → Result: Khorana 0（Risk: Low risk）