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🧬 REACH-B HCC Risk Score

UseWhen to use: non-cirrhotic chronic hepatitis B risk counseling / surveillance planning.

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StrataHigher scores → higher published HCC risk percentages.

LimitsWhen not to use: established cirrhosis staging alone. · Pitfall: ignoring antiviral treatment effect. · Pair with PAGE-B on NAs.

SourceYang HI et al. REACH-B

Runs locally in your browser (no PHI uploaded). For licensed clinicians — not a substitute for clinical judgement.
Stored on this device for revisit reminders

This-shift next steps

After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.

Scene next step
📋liverOpen scene pack →
Related scores
Matching pathway
🧭cholangitisOpen pathway →
Score + version; reference only — not a substitute for care · no HIS write

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Methodology · worked example, guidelines & full notes
Clinical takeaway

0–17.

When to use

When to use: non-cirrhotic chronic hepatitis B risk counseling / surveillance planning.

How it works

Sex+age+ALT+HBeAg+HBV DNA points (0–17).

Key points

  • 0–17.
  • DNA points non-linear.
  • Next: US surveillance plan.

References

  • Yang HI et al. REACH-B

Worked calculation

The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.

SexFemale (0)
Age band45–49 (+3)
ALT (U/L)15–44 (+1)
HBeAgNegative (0)
HBV DNA (copies/mL)10000–99999 (+5)

→REACH-B9/17

  • ≈3-y HCC：1.8%
  • ≈5-y HCC：2.7%
  • ≈10-y HCC：6.4%
SexFemale (0)
Age band30–34 (0)
ALT (U/L)<15 (0)
HBeAgNegative (0)
HBV DNA (copies/mL)<300 / undetectable (0)

→REACH-B0/17

  • ≈3-y HCC：0%
  • ≈5-y HCC：0%
  • ≈10-y HCC：0.1%
Verification & sources · governance
FAQ

Frequently asked questions

Does REACH-B HCC Risk Score upload patient data? Where is it calculated?
Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
How is REACH-B HCC Risk Score calculated in practice? Can you show a worked example?
Inputs: Sex Female (0), Age band 45–49 (+3), ALT (U/L) 15–44 (+1), HBeAg Negative (0), HBV DNA (copies/mL) 10000–99999 (+5) → Result: REACH-B 9 /17（≈3-y HCC: 1.8%, ≈5-y HCC: 2.7%, ≈10-y HCC: 6.4%） Inputs: Sex Female (0), Age band 30–34 (0), ALT (U/L) <15 (0), HBeAg Negative (0), HBV DNA (copies/mL) <300 / undetectable (0) → Result: REACH-B 0 /17（≈3-y HCC: 0%, ≈5-y HCC: 0%, ≈10-y HCC: 0.1%）
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