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🫀 R Factor (Liver Injury Pattern)

UseWhen to use: suspected drug-induced liver injury pattern typing (CIOMS/RUCAM-style).

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StrataR≥5 hepatocellular; R≤2 cholestatic; otherwise mixed — guides causality evaluation.

LimitsWhen not to use: missing lab-specific ULNs. · Pitfall: using AST without noting substitution. · Not a DILI diagnosis alone.

SourceCIOMS R-factor liver-injury pattern ratio

Runs locally in your browser (no PHI uploaded). For licensed clinicians — not a substitute for clinical judgement.
Stored on this device for revisit reminders

This-shift next steps

After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.

Paste the link in Slack, Teams, X, or LinkedIn — the preview image comes from this page’s Open Graph card.

Methodology · worked example, guidelines & full notes
Clinical takeaway

(ALT/ULN)/(ALP/ULN).

When to use

When to use: suspected drug-induced liver injury pattern typing (CIOMS/RUCAM-style).

How it works

R = (ALT/ULN_ALT) / (ALP/ULN_ALP).

Key points

  • (ALT/ULN)/(ALP/ULN).
  • CIOMS pattern.
  • Next: RUCAM / drug timeline.

References

  • CIOMS R-factor liver-injury pattern ratio

Worked calculation

The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.

ALT400 U/L
ALT ULN40 U/L
ALP120 U/L
ALP ULN120 U/L

→R factor10.00

  • ALT×ULN：10.00
  • ALP×ULN：1.00
  • Cue：R ≥5 — hepatocellular pattern cue
Verification & sources · governance
FAQ

Frequently asked questions

Does R Factor (Liver Injury Pattern) upload patient data? Where is it calculated?
Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
How is R Factor (Liver Injury Pattern) calculated in practice? Can you show a worked example?
Inputs: ALT 400 U/L, ALT ULN 40 U/L, ALP 120 U/L, ALP ULN 120 U/L → Result: R factor 10.00（ALT×ULN: 10.00, ALP×ULN: 1.00, Cue: R ≥5 — hepatocellular pattern cue）
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