💊 Opioid Equianalgesic Converter (OME)
UseCalculating daily oral morphine milligram equivalents (MME) for oral opioids.
StrataMME = daily dose × CDC 2022 conversion factor (PMID 36327391; oral: morphine 1, oxycodone 1.5, hydromorphone …
LimitsMethadone, fentanyl, buprenorphine and IV forms are not on this page. · Factors are not intended for converting between opioids (CDC 2022). · For licensed clinicians; does not replace clinical judgement.
SourceDowell D, et al. CDC Clinical Practice Guideline for Prescribing Opioids for Pain — United States, …
This-shift next steps
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Methodology · worked example, guidelines & full notes
Oral hydromorphone factor 5.0 (CDC 2022).
When to use
Calculating daily oral morphine milligram equivalents (MME) for oral opioids.
How it works
MME = daily dose × factor (CDC 2022): morphine 1, oxycodone 1.5, hydromorphone 5.0, hydrocodone 1, oxymorphone 3, codeine 0.15, tramadol 0.2, tapentadol 0.4.
Key points
- Oral hydromorphone factor 5.0 (CDC 2022).
- Reassess before increasing to ≥50 MME/day.
- Factors are not intended for converting between opioids.
References
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Current drug (oral) | Hydrocodone — oral |
|---|---|
| Current total daily dose | 30 mg/day |
| Comparison drug (oral) | Hydrocodone — oral |
→MME30mg/day
- Substitution：Hydrocodone — oral 30 × 1 = 30 MME
- Arithmetic equivalent (unadjusted)：30 ÷ 1 = 30 mg (Hydrocodone — oral)
| Current drug (oral) | Tapentadol — oral |
|---|---|
| Current total daily dose | 30 mg/day |
| Comparison drug (oral) | Tapentadol — oral |
→MME12mg/day
- Substitution：Tapentadol — oral 30 × 0.4 = 12 MME
- Arithmetic equivalent (unadjusted)：12 ÷ 0.4 = 30 mg (Tapentadol — oral)
Verification & sources · governance
FAQ
Frequently asked questions
- Does Opioid Equianalgesic Converter (OME) upload patient data? Where is it calculated?
- Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
- How is Opioid Equianalgesic Converter (OME) calculated in practice? Can you show a worked example?
- Inputs: Current drug (oral) Hydrocodone — oral, Current total daily dose 30 mg/day, Comparison drug (oral) Hydrocodone — oral → Result: MME 30 mg/day（Substitution: Hydrocodone — oral 30 × 1 = 30 MME, Arithmetic equivalent (unadjusted): 30 ÷ 1 = 30 mg (Hydrocodone — oral)） Inputs: Current drug (oral) Tapentadol — oral, Current total daily dose 30 mg/day, Comparison drug (oral) Tapentadol — oral → Result: MME 12 mg/day（Substitution: Tapentadol — oral 30 × 0.4 = 12 MME, Arithmetic equivalent (unadjusted): 12 ÷ 0.4 = 30 mg (Tapentadol — oral)）