🫀 MELD-XI (Excluding INR)
UseEnter total bilirubin and serum creatinine; the tool applies the standard bounds and returns the MELD-XI scor…
SourceHeuman DM, et al. MELD-XI: a rational approach to sickest first liver transplantation in cirrhotic …
This-shift next steps
After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.
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Methodology · worked example, guidelines & full notes
MELD-XI is most useful in mechanical-valve, VAD, or advanced heart-failure patients where warfarin distorts the INR term (original synthesis · not guideline verbatim).
When to use
Enter total bilirubin and serum creatinine; the tool applies the standard bounds and returns the MELD-XI score.
How it works
MELD-XI = 5.11 × ln(bilirubin mg/dL) + 11.76 × ln(creatinine mg/dL) + 9.44; bilirubin and creatinine <1 set to 1, creatinine capped at 4 mg/dL.
Key points
- MELD-XI is most useful in mechanical-valve, VAD, or advanced heart-failure patients where warfarin distorts the INR term (original synthesis · not guideline verbatim).
- Higher scores predict worse survival in both hepatic and cardiac populations, including pre-transplant candidates.
- Because INR is dropped, MELD-XI can underestimate coagulopathy from intrinsic liver synthetic failure.
References
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Total bilirubin | 34 μmol/L |
|---|---|
| Serum creatinine | 90 μmol/L |
→MELD-XI13.2
- Bilirubin:2 mg/dL
- Creatinine:1 mg/dL (capped at 4)
Verification & sources · governance
FAQ
Frequently asked questions
- What are the limits and cautions when using MELD-XI (Excluding INR)?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- Does MELD-XI (Excluding INR) upload patient data? Where is it calculated?
- Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
- How is MELD-XI (Excluding INR) calculated in practice? Can you show a worked example?
- Inputs: Total bilirubin 34 μmol/L, Serum creatinine 90 μmol/L → Result: MELD-XI 13.2(Bilirubin: 2 mg/dL, Creatinine: 1 mg/dL (capped at 4))