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🧫 Hepatic Steatosis Index (HSI)

UseWhen to use: metabolic-risk adults when ALT, AST, BMI, sex, and DM status known.

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Strata<30 less likely; >36 more likely; 30–36 indeterminate.

LimitsWhen not to use: as fibrosis staging. · Pitfall: acute hepatitis distorting ALT/AST. · Pair with FIB-4/FLI/elastography.

SourceLee JH et al. Hepatic Steatosis Index

Runs locally in your browser (no PHI uploaded). For licensed clinicians — not a substitute for clinical judgement.
Stored on this device for revisit reminders

This-shift next steps

After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.

Scene next step
📋liverOpen scene pack →
Related scores
Matching pathway
🧭cholangitisOpen pathway →
Score + version; reference only — not a substitute for care · no HIS write

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Methodology · worked example, guidelines & full notes
Clinical takeaway

ALT/AST + BMI.

When to use

When to use: metabolic-risk adults when ALT, AST, BMI, sex, and DM status known.

How it works

HSI=8×(ALT/AST)+BMI+2(female)+2(diabetes).

Key points

  • ALT/AST + BMI.
  • <30 / >36.
  • Next: metabolic / FibroScan.

References

  • Lee JH et al. Hepatic Steatosis Index

Worked calculation

The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.

ALT45 U/L
AST30 U/L
BMI28 kg/m²
SexMale (0)
Diabetes mellitusNo (0)

→HSI40.0

  • Band：>36 — steatosis more likely (rule-in band)
  • ALT/AST：1.50
ALT45 U/L
AST30 U/L
BMI28 kg/m²
SexFemale (+2)
Diabetes mellitusYes (+2)

→HSI44.0

  • Band：>36 — steatosis more likely (rule-in band)
  • ALT/AST：1.50
Verification & sources · governance
FAQ

Frequently asked questions

Does Hepatic Steatosis Index (HSI) upload patient data? Where is it calculated?
Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
How is Hepatic Steatosis Index (HSI) calculated in practice? Can you show a worked example?
Inputs: ALT 45 U/L, AST 30 U/L, BMI 28 kg/m², Sex Male (0), Diabetes mellitus No (0) → Result: HSI 40.0（Band: >36 — steatosis more likely (rule-in band), ALT/AST: 1.50） Inputs: ALT 45 U/L, AST 30 U/L, BMI 28 kg/m², Sex Female (+2), Diabetes mellitus Yes (+2) → Result: HSI 44.0（Band: >36 — steatosis more likely (rule-in band), ALT/AST: 1.50）
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