🧫 GALAD Model (HCC Detection)
UseWhen to use: chronic liver disease with AFP, AFP-L3%, and DCP available.
StrataCommon cut-off −0.63 triage imaging; not histologic proof.
LimitsWhen not to use: replacing multiphase CT/MRI when already indicated. · Pitfall: AFP or DCP ≤0 (log undefined). · Not a sole HCC diagnosis.
SourceGALAD model (Johnson et al.)
This-shift next steps
After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.
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Methodology · worked example, guidelines & full notes
Five inputs.
When to use
When to use: chronic liver disease with AFP, AFP-L3%, and DCP available.
How it works
−10.08 + 0.09×age + 1.67×male + 2.34×log10(AFP) + 0.04×AFP-L3 + 1.33×log10(DCP).
Key points
- Five inputs.
- Linear predictor.
- Next: imaging pathway.
References
- GALAD model (Johnson et al.)
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Sex | Female (0) |
|---|---|
| Age (years) | 62 y |
| AFP (ng/mL) | 12 ng/mL |
| AFP-L3 (%) | 5 % |
| DCP / PIVKA-II (ng/mL) | 20 ng/mL |
→GALAD-0.04
- Cue：At/above −0.63 — higher HCC probability; pursue imaging per protocol
| Sex | Male (+1 in model) |
|---|---|
| Age (years) | 62 y |
| AFP (ng/mL) | 12 ng/mL |
| AFP-L3 (%) | 5 % |
| DCP / PIVKA-II (ng/mL) | 20 ng/mL |
→GALAD1.63
- Cue：At/above −0.63 — higher HCC probability; pursue imaging per protocol
Verification & sources · governance
FAQ
Frequently asked questions
- Does GALAD Model (HCC Detection) upload patient data? Where is it calculated?
- Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
- How is GALAD Model (HCC Detection) calculated in practice? Can you show a worked example?
- Inputs: Sex Female (0), Age (years) 62 y, AFP (ng/mL) 12 ng/mL, AFP-L3 (%) 5 %, DCP / PIVKA-II (ng/mL) 20 ng/mL → Result: GALAD -0.04（Cue: At/above −0.63 — higher HCC probability; pursue imaging per protocol） Inputs: Sex Male (+1 in model), Age (years) 62 y, AFP (ng/mL) 12 ng/mL, AFP-L3 (%) 5 %, DCP / PIVKA-II (ng/mL) 20 ng/mL → Result: GALAD 1.63（Cue: At/above −0.63 — higher HCC probability; pursue imaging per protocol）