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🧫 Fibrotic NASH Index (FNI)

UseWhen to use: metabolic-risk / NAFLD patients when labs (AST, HbA1c, HDL) are available.

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Strata<0.10 lower fibrotic-NASH probability; ≥0.33 higher — consider elastography/hepatology.

LimitsWhen not to use: as biopsy replacement. · Pitfall: HDL entered in mmol/L without conversion. · Pair with FIB-4 / imaging fibrosis tests.

SourceTavaglione et al. Fibrotic NASH Index

Runs locally in your browser (no PHI uploaded). For licensed clinicians — not a substitute for clinical judgement.
Stored on this device for revisit reminders

This-shift next steps

After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.

Scene next step
📋liverOpen scene pack →
Related scores
Matching pathway
🧭cholangitisOpen pathway →
Score + version; reference only — not a substitute for care · no HIS write

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Methodology · worked example, guidelines & full notes
Clinical takeaway

AST + HbA1c + HDL.

When to use

When to use: metabolic-risk / NAFLD patients when labs (AST, HbA1c, HDL) are available.

How it works

FNI = e^p/(1+e^p); p=−10.33+2.54·ln(AST)+3.86·ln(HbA1c)−1.66·ln(HDL mg/dL).

Key points

  • AST + HbA1c + HDL.
  • <0.10 / ≥0.33 cutoffs.
  • Next: FIB-4 / FibroScan.

References

  • Tavaglione et al. Fibrotic NASH Index

Worked calculation

The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.

AST45 U/L
HbA1c6.2 %
HDL cholesterol40 mg/dL

→FNI0.564

  • Band：≥0.33 rule-in / higher-risk band — specialist pathway
  • HDL unit：Use mg/dL (mmol/L × 38.67 ≈ mg/dL)
Verification & sources · governance
FAQ

Frequently asked questions

Does Fibrotic NASH Index (FNI) upload patient data? Where is it calculated?
Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
How is Fibrotic NASH Index (FNI) calculated in practice? Can you show a worked example?
Inputs: AST 45 U/L, HbA1c 6.2 %, HDL cholesterol 40 mg/dL → Result: FNI 0.564（Band: ≥0.33 rule-in / higher-risk band — specialist pathway, HDL unit: Use mg/dL (mmol/L × 38.67 ≈ mg/dL)）
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