🫁 CLIF Organ Failure Score
UseWhen to use: acutely decompensated cirrhosis when assessing organ failures.
StrataGrade-3 organs define organ failures used in EF-CLIF ACLF staging.
LimitsWhen not to use: non-cirrhotic multi-organ failure alone. · Pitfall: unit mismatches (mg/dL). · Not a sole transplant list decision.
SourceEF-CLIF organ failure grades (CLIF-C ACLF system)
This-shift next steps
After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.
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Methodology · worked example, guidelines & full notes
Six organs.
When to use
When to use: acutely decompensated cirrhosis when assessing organ failures.
How it works
Liver, kidney, brain, coagulation, circulation, respiration each 1–3 (sum 6–18).
Key points
- Six organs.
- Feeds CLIF-C ACLF.
- Next: CLIF-C ACLF / AD tools.
References
- EF-CLIF organ failure grades (CLIF-C ACLF system)
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Liver (bilirubin) | 2 — 6–<12 mg/dL |
|---|---|
| Kidney | 2 — Cr 2–<3.5 mg/dL |
| Brain (HE grade) | 2 — HE 1–2 |
| Coagulation (INR) | 2 — INR 2–<2.5 |
| Circulation | 2 — MAP <70, no pressors |
| Respiration (PaO₂/FiO₂ or SpO₂/FiO₂) | 2 — P/F ≤300–>200 or S/F ≤357–>214 |
→CLIF-OF sum12/18
- Grade-3 organs：0
- Cue：No grade-3 organ failure on this entry
| Liver (bilirubin) | 1 — <6 mg/dL |
|---|---|
| Kidney | 1 — Cr <2 mg/dL |
| Brain (HE grade) | 1 — HE 0 |
| Coagulation (INR) | 1 — INR <2 |
| Circulation | 1 — MAP ≥70, no pressors |
| Respiration (PaO₂/FiO₂ or SpO₂/FiO₂) | 1 — P/F >300 or S/F >357 |
→CLIF-OF sum6/18
- Grade-3 organs：0
- Cue：No grade-3 organ failure on this entry
Verification & sources · governance
FAQ
Frequently asked questions
- Does CLIF Organ Failure Score upload patient data? Where is it calculated?
- Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
- How is CLIF Organ Failure Score calculated in practice? Can you show a worked example?
- Inputs: Liver (bilirubin) 2 — 6–<12 mg/dL, Kidney 2 — Cr 2–<3.5 mg/dL, Brain (HE grade) 2 — HE 1–2, Coagulation (INR) 2 — INR 2–<2.5, Circulation 2 — MAP <70, no pressors, Respiration (PaO₂/FiO₂ or SpO₂/FiO₂) 2 — P/F ≤300–>200 or S/F ≤357–>214 → Result: CLIF-OF sum 12 /18（Grade-3 organs: 0, Cue: No grade-3 organ failure on this entry） Inputs: Liver (bilirubin) 1 — <6 mg/dL, Kidney 1 — Cr <2 mg/dL, Brain (HE grade) 1 — HE 0, Coagulation (INR) 1 — INR <2, Circulation 1 — MAP ≥70, no pressors, Respiration (PaO₂/FiO₂ or SpO₂/FiO₂) 1 — P/F >300 or S/F >357 → Result: CLIF-OF sum 6 /18（Grade-3 organs: 0, Cue: No grade-3 organ failure on this entry）