🩸 Arterial Oxygen Content (CaO₂)
UseQuantify oxygen content for delivery and shunt calculations.
SourceMarino PL. The ICU Book
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Methodology · worked example, guidelines & full notes
Most oxygen is bound to haemoglobin; dissolved O₂ is small.
When to use
Quantify oxygen content for delivery and shunt calculations.
How it works
CaO₂ = 1.34 × Hb × SaO₂ + 0.0031 × PaO₂. Normal ≈ 18–20 mL O₂/dL.
Key points
- Most oxygen is bound to haemoglobin; dissolved O₂ is small.
- Anaemia lowers content despite a normal SaO₂.
- Feeds into DO₂ and oxygen extraction calculations.
References
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Haemoglobin | 15 g/dL |
|---|---|
| SaO₂ | 98 % |
| PaO₂ | 100 mmHg |
→CaO₂20.0mL O₂/dL
- Bound to Hb:19.7 mL/dL
- Dissolved:0.31 mL/dL
- Formula:1.34 × Hb × SaO₂ + 0.0031 × PaO₂
Verification & sources · governance
FAQ
Frequently asked questions
- What are the limits and cautions when using Arterial Oxygen Content (CaO₂)?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- Does Arterial Oxygen Content (CaO₂) upload patient data? Where is it calculated?
- Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
- How is Arterial Oxygen Content (CaO₂) calculated in practice? Can you show a worked example?
- Inputs: Haemoglobin 15 g/dL, SaO₂ 98 %, PaO₂ 100 mmHg → Result: CaO₂ 20.0 mL O₂/dL(Bound to Hb: 19.7 mL/dL, Dissolved: 0.31 mL/dL, Formula: 1.34 × Hb × SaO₂ + 0.0031 × PaO₂)