🔬 Prostate PI-RADS v2.1 Score
UseScore a prostate mpMRI lesion and decide on MRI-targeted biopsy.
SourceTurkbey B, et al. PI-RADS v2.1: 2019 Update. Eur Urol 2019
This-shift next steps
After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.
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Methodology · worked example, guidelines & full notes
DCE only arbitrates the peripheral-zone DWI-3 lesion.
When to use
Score a prostate mpMRI lesion and decide on MRI-targeted biopsy.
How it works
TZ is T2-dominant (T2 = 2 + DWI ≥ 4→ 3, T2 = 3 + DWI = 5→ 4). Categories 1–5.
Key points
- DCE only arbitrates the peripheral-zone DWI-3 lesion.
- PI-RADS 1–2 carry low likelihood of clinically significant cancer.
- PI-RADS 4–5 warrant MRI-targeted biopsy.
References
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Lesion zone | Peripheral zone PZ (DWI dominant) |
|---|---|
| DWI/ADC score | 3 |
| T2WI score | 3 |
| DCE dynamic enhancement | Positive (focal early enhancement at the suspicious lesion) |
→ScorePI-RADS 4
- Score:PI-RADS 4 (clinically significant cancer detection rate ~53%)
- Basis:PZ is DWI-dominant; DWI = 3 + DCE positive
- Management:Clinically significant cancer likely: MRI-targeted biopsy recommended
| Lesion zone | Peripheral zone PZ (DWI dominant) |
|---|---|
| DWI/ADC score | 1 |
| T2WI score | 1 |
| DCE dynamic enhancement | Positive (focal early enhancement at the suspicious lesion) |
→ScorePI-RADS 1
- Score:PI-RADS 1 (clinically significant cancer detection rate ~3%)
- Basis:PZ is DWI-dominant; DWI = 1 → PI-RADS 1
- Management:Clinically significant cancer highly unlikely: generally no biopsy; follow PSA/clinical
Verification & sources · governance
FAQ
Frequently asked questions
- What are the limits and cautions when using Prostate PI-RADS v2.1 Score?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- Does Prostate PI-RADS v2.1 Score upload patient data? Where is it calculated?
- Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
- How is Prostate PI-RADS v2.1 Score calculated in practice? Can you show a worked example?
- Inputs: Lesion zone Peripheral zone PZ (DWI dominant), DWI/ADC score 3, T2WI score 3, DCE dynamic enhancement Positive (focal early enhancement at the suspicious lesion) → Result: Score PI-RADS 4(Score: PI-RADS 4 (clinically significant cancer detection rate ~53%), Basis: PZ is DWI-dominant; DWI = 3 + DCE positive, Management: Clinically significant cancer likely: MRI-targeted biopsy recommended) Inputs: Lesion zone Peripheral zone PZ (DWI dominant), DWI/ADC score 1, T2WI score 1, DCE dynamic enhancement Positive (focal early enhancement at the suspicious lesion) → Result: Score PI-RADS 1(Score: PI-RADS 1 (clinically significant cancer detection rate ~3%), Basis: PZ is DWI-dominant; DWI = 1 → PI-RADS 1, Management: Clinically significant cancer highly unlikely: generally no biopsy; follow PSA/clinical)