⏱️ Nodule Volume & Volume Doubling Time (VDT)
UseAssessing growth of lung nodules on follow-up CT; also usable for other lesions.
SourceCallister MEJ, et al. BTS guidelines. Thorax 2015;70 Suppl 2:ii1-ii54
This-shift next steps
After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.
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Methodology · worked example, guidelines & full notes
Growth = ≥25% volume increase.
When to use
Assessing growth of lung nodules on follow-up CT; also usable for other lesions.
How it works
V = π/6·a·b·c (sphere if only one diameter); VDT = Δt·ln2 / ln(V2/V1); change = (V2−V1)/V1.
Key points
- Growth = ≥25% volume increase.
- Solid VDT <400 days is suspicious.
- 400–600 days indeterminate.
- Subsolid nodules can have long VDTs.
References
- [Guideline / primary source]Callister MEJ, et al. BTS guidelines. Thorax 2015;70 Suppl 2:ii1-ii54
- Horeweg N, et al. Lancet Oncol 2014;15:1332-1341 (NELSON)
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Earlier volume (software; blank to use diameters) | 250 mm³ |
|---|---|
| Current volume (software; blank to use diameters) | 400 mm³ |
| Earlier long axis | 8 mm |
| Current long axis | 10 mm |
| Interval between scans | 90 days |
| Nodule type | Solid |
→Volume doubling time133days
- Earlier / current volume：250 / 400 mm³ (software volumes)
- Volume change：+60.0%
- Reading：Significant growth: VDT <400 days (NELSON positive)
Verification & sources · governance
FAQ
Frequently asked questions
- What are the limits and cautions when using Nodule Volume & Volume Doubling Time (VDT)?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- Does Nodule Volume & Volume Doubling Time (VDT) upload patient data? Where is it calculated?
- Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
- How is Nodule Volume & Volume Doubling Time (VDT) calculated in practice? Can you show a worked example?
- Inputs: Earlier volume (software; blank to use diameters) 250 mm³, Current volume (software; blank to use diameters) 400 mm³, Earlier long axis 8 mm, Current long axis 10 mm, Interval between scans 90 days, Nodule type Solid → Result: Volume doubling time 133 days（Earlier / current volume: 250 / 400 mm³ (software volumes), Volume change: +60.0%, Reading: Significant growth: VDT <400 days (NELSON positive)）