🧪 Martin/Hopkins LDL-C Estimate
UseWhen to use: lipid panels where Friedewald may mis-estimate (TG ~150–400 mg/dL).
StrataCompare with risk-based LDL goals; show Friedewald only as reference.
LimitsWhen not to use: as sole Type III dyslipidemia workup. · Pitfall: entering mmol/L without conversion. · Very high TG: prefer direct LDL / apoB.
SourceMartin SS et al. LDL-C estimation
This-shift next steps
After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.
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Methodology · worked example, guidelines & full notes
Novel CF ≠ 5.
When to use
When to use: lipid panels where Friedewald may mis-estimate (TG ~150–400 mg/dL).
How it works
LDL-C = TC − HDL-C − TG/CF (CF from TG × non-HDL table).
Key points
- Novel CF ≠ 5.
- Better than Friedewald mid-TG.
- Next: ASCVD risk / Rx.
References
- Martin SS et al. LDL-C estimation
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Total cholesterol | 200 mg/dL |
|---|---|
| HDL-C | 45 mg/dL |
| Triglycerides | 180 mg/dL |
→LDL-C (Martin)131.0mg/dL
- Novel factor：7.5
- Non-HDL-C：155.0 mg/dL
- Friedewald (ref)：119.0 mg/dL
Verification & sources · governance
FAQ
Frequently asked questions
- Does Martin/Hopkins LDL-C Estimate upload patient data? Where is it calculated?
- Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
- How is Martin/Hopkins LDL-C Estimate calculated in practice? Can you show a worked example?
- Inputs: Total cholesterol 200 mg/dL, HDL-C 45 mg/dL, Triglycerides 180 mg/dL → Result: LDL-C (Martin) 131.0 mg/dL（Novel factor: 7.5, Non-HDL-C: 155.0 mg/dL, Friedewald (ref): 119.0 mg/dL）