📊 Lesion Follow-up Comparison (change, doubling time, RECIST target response)
UseOncology follow-up, response assessment and re-checks of incidental lesions.
SourceEisenhauer EA, et al. Eur J Cancer 2009;45:228-247 (RECIST 1.1)
This-shift next steps
After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.
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Methodology · worked example, guidelines & full notes
PR: ≥30% decrease from baseline.
When to use
Oncology follow-up, response assessment and re-checks of incidental lesions.
How it works
Change = (current − baseline)/baseline; PR ≤ −30% vs baseline; PD ≥ +20% vs nadir and ≥5 mm; doubling time ≈ Δt·ln2 / [3·ln(D2/D1)].
Key points
- PR: ≥30% decrease from baseline.
- PD: ≥20% and ≥5 mm increase from nadir.
- Nodes measured in short axis.
- Assess non-target and new lesions separately.
References
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Lesion 1 baseline | 32 mm |
|---|---|
| Lesion 1 current | 24 mm |
| Baseline-to-current interval (for doubling time; optional) | 84 days |
→Target response (RECIST 1.1)SD
- Lesion 1：32 → 24 mm (-8.0 mm, -25.0%)
- Sum of diameters：baseline 32.0 / nadir 32.0 / current 24.0 mm
- vs baseline / vs nadir：-25.0% / -25.0%
Verification & sources · governance
FAQ
Frequently asked questions
- What are the limits and cautions when using Lesion Follow-up Comparison (change, doubling time, RECIST target response)?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- Does Lesion Follow-up Comparison (change, doubling time, RECIST target response) upload patient data? Where is it calculated?
- Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
- How is Lesion Follow-up Comparison (change, doubling time, RECIST target response) calculated in practice? Can you show a worked example?
- Inputs: Lesion 1 baseline 32 mm, Lesion 1 current 24 mm, Baseline-to-current interval (for doubling time; optional) 84 days → Result: Target response (RECIST 1.1) SD（Lesion 1: 32 → 24 mm (-8.0 mm, -25.0%), Sum of diameters: baseline 32.0 / nadir 32.0 / current 24.0 mm, vs baseline / vs nadir: -25.0% / -25.0%）