🩸 ISTH DIC Score (Overt DIC)
UseConfirm overt DIC in a patient with a predisposing condition.
SourceTaylor FB, et al. (ISTH) Thromb Haemost 2001
This-shift next steps
After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.
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Methodology · worked example, guidelines & full notes
Only apply when an underlying DIC-associated disorder is present.
When to use
Confirm overt DIC in a patient with a predisposing condition.
How it works
Platelets, D-dimer/FDP, prolonged PT and fibrinogen are scored; total ≥ 5 is compatible with overt DIC.
Key points
- Only apply when an underlying DIC-associated disorder is present.
- Score < 5 does not exclude evolving (non-overt) DIC — repeat.
References
- [Guideline / primary source]Taylor FB, et al. (ISTH) Thromb Haemost 2001
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Platelet count | 50–100 (1) |
|---|---|
| Fibrin marker (D-dimer/FDP) | Moderate increase (2) |
| PT prolongation | 3–6 s (1) |
| Fibrinogen | ≥ 1 g/L (0) |
→ISTH DIC4/8
- Interpretation：< 5 — not suggestive of overt DIC; consider repeating if suspicion persists.
| Platelet count | > 100 (0) |
|---|---|
| Fibrin marker (D-dimer/FDP) | No increase (0) |
| PT prolongation | < 3 s (0) |
| Fibrinogen | ≥ 1 g/L (0) |
→ISTH DIC0/8
- Interpretation：< 5 — not suggestive of overt DIC; consider repeating if suspicion persists.
Verification & sources · governance
FAQ
Frequently asked questions
- What are the limits and cautions when using ISTH DIC Score (Overt DIC)?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- Does ISTH DIC Score (Overt DIC) upload patient data? Where is it calculated?
- Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
- How is ISTH DIC Score (Overt DIC) calculated in practice? Can you show a worked example?
- Inputs: Platelet count 50–100 (1), Fibrin marker (D-dimer/FDP) Moderate increase (2), PT prolongation 3–6 s (1), Fibrinogen ≥ 1 g/L (0) → Result: ISTH DIC 4 /8（Interpretation: < 5 — not suggestive of overt DIC; consider repeating if suspicion persists.） Inputs: Platelet count > 100 (0), Fibrin marker (D-dimer/FDP) No increase (0), PT prolongation < 3 s (0), Fibrinogen ≥ 1 g/L (0) → Result: ISTH DIC 0 /8（Interpretation: < 5 — not suggestive of overt DIC; consider repeating if suspicion persists.）