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🔥 Inflammatory Marker Interpretation

UseUse the trend rather than single values; PCT supports antibiotic stewardship and ferritin doubles as an acute…

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SourceProcalcitonin-guided antibiotic stewardship and acute-phase reactant interpretation

Runs locally in your browser (no PHI uploaded). For licensed clinicians — not a substitute for clinical judgement.
Stored on this device for revisit reminders

This-shift next steps

After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.

Scene next step
📋labsOpen scene pack →
Related scores
Score + version; reference only — not a substitute for care · no HIS write

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Methodology · worked example, guidelines & full notes
Clinical takeaway

All inflammatory markers are non-specific.

When to use

Use the trend rather than single values; PCT supports antibiotic stewardship and ferritin doubles as an acute-phase reactant.

How it works

PCT: < 0.25 argues against bacterial (lower respiratory), > 0.5 possible sepsis, > 2 high-risk. CRP half-life ≈ 19 h.

Key points

  • All inflammatory markers are non-specific.
  • PCT supports stewardship but is not a standalone decision.
  • Ferritin is both an iron-store marker and an acute-phase reactant — interpret with CRP/TSAT.
  • Very high ferritin: consider adult Still disease or HLH (HScore).

References

Worked calculation

The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.

ViewProcalcitonin (PCT)

→InterpretationProcalcitonin (PCT)

  • Behaviour：Rises in bacterial infection/sepsis, lower in viral/localised inflammation
  • Common cut-offs：< 0.25 argues against bacterial (lower respiratory); > 0.5 possible sepsis; > 2 high-risk (lab-dependent)
  • Use：Antibiotic start/stop support (stewardship), not a standalone decision
ViewCRP/ESR

→InterpretationCRP / ESR

  • CRP：Acute-phase, responds fast (half-life ≈ 19 h); often higher in bacterial infection; the trend beats a single value
  • ESR：Rises slowly, affected by anaemia/globulins; used to follow rheumatic disease/PMR/GCA
  • Cue：Both are non-specific — correlate clinically
Verification & sources · governance
FAQ

Frequently asked questions

What are the limits and cautions when using Inflammatory Marker Interpretation?
For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
Does Inflammatory Marker Interpretation upload patient data? Where is it calculated?
Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
How is Inflammatory Marker Interpretation calculated in practice? Can you show a worked example?
Inputs: View Procalcitonin (PCT) → Result: Interpretation Procalcitonin (PCT)（Behaviour: Rises in bacterial infection/sepsis, lower in viral/localised inflammation, Common cut-offs: < 0.25 argues against bacterial (lower respiratory); > 0.5 possible sepsis; > 2 high-risk (lab-dependent), Use: Antibiotic start/stop support (stewardship), not a standalone decision） Inputs: View CRP/ESR → Result: Interpretation CRP / ESR（CRP: Acute-phase, responds fast (half-life ≈ 19 h); often higher in bacterial infection; the trend beats a single value, ESR: Rises slowly, affected by anaemia/globulins; used to follow rheumatic disease/PMR/GCA, Cue: Both are non-specific — correlate clinically）
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