🧬 IMDC (Heng) Metastatic RCC Risk
UseWhen to use: before systemic therapy for metastatic clear-cell RCC.
Strata0 favorable, 1–2 intermediate, ≥3 poor risk.
LimitsWhen not to use: localized RCC pathways alone. · Pitfall: wrong ULN assay. · Not a sole regimen pick.
SourceIMDC / Heng metastatic RCC risk model
This-shift next steps
After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.
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Methodology · worked example, guidelines & full notes
Six factors.
When to use
When to use: before systemic therapy for metastatic clear-cell RCC.
How it works
One point each: KPS <80%, Dx-to-Rx <1 y, Hb <LLN, Ca >ULN, neutrophils >ULN, platelets >ULN.
Key points
- Six factors.
- Three risk groups.
- Next: IMDC-guided systemic options.
References
- IMDC / Heng metastatic RCC risk model
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Karnofsky performance status <80% | No (KPS ≥80) |
|---|---|
| Time from diagnosis to systemic therapy <1 year | No |
| Hemoglobin < lower limit of normal | No |
| Corrected calcium > upper limit of normal | No |
| Neutrophils > upper limit of normal | No |
| Platelets > upper limit of normal | No |
→IMDC factors0/6
- Risk group：Favorable (0 factors)
| Karnofsky performance status <80% | Yes (KPS <80) (+1) |
|---|---|
| Time from diagnosis to systemic therapy <1 year | Yes (+1) |
| Hemoglobin < lower limit of normal | Yes (+1) |
| Corrected calcium > upper limit of normal | Yes (+1) |
| Neutrophils > upper limit of normal | Yes (+1) |
| Platelets > upper limit of normal | Yes (+1) |
→IMDC factors6/6
- Risk group：Poor (≥3 factors)
Verification & sources · governance
FAQ
Frequently asked questions
- Does IMDC (Heng) Metastatic RCC Risk upload patient data? Where is it calculated?
- Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
- How is IMDC (Heng) Metastatic RCC Risk calculated in practice? Can you show a worked example?
- Inputs: Karnofsky performance status <80% No (KPS ≥80), Time from diagnosis to systemic therapy <1 year No, Hemoglobin < lower limit of normal No, Corrected calcium > upper limit of normal No, Neutrophils > upper limit of normal No, Platelets > upper limit of normal No → Result: IMDC factors 0 /6（Risk group: Favorable (0 factors)） Inputs: Karnofsky performance status <80% Yes (KPS <80) (+1), Time from diagnosis to systemic therapy <1 year Yes (+1), Hemoglobin < lower limit of normal Yes (+1), Corrected calcium > upper limit of normal Yes (+1), Neutrophils > upper limit of normal Yes (+1), Platelets > upper limit of normal Yes (+1) → Result: IMDC factors 6 /6（Risk group: Poor (≥3 factors)）