Home › Clinical Tools › HOMA-IR

🩸 HOMA-IR (Insulin Resistance)

UseAssess insulin resistance in metabolic and endocrine work-ups.

Loading calculator…

SourceMatthews DR, et al. Diabetologia 1985

Runs locally in your browser (no PHI uploaded). For licensed clinicians — not a substitute for clinical judgement.
Stored on this device for revisit reminders

This-shift next steps

After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.

Scene next step
📋endocrineOpen scene pack →
Related scores
Matching pathway
🧭dkaOpen pathway →
Score + version; reference only — not a substitute for care · no HIS write

Paste the link in Slack, Teams, X, or LinkedIn — the preview image comes from this page’s Open Graph card.

Methodology · worked example, guidelines & full notes
Clinical takeaway

Cut-offs vary by population and assay (~2.5–2.9).

When to use

Assess insulin resistance in metabolic and endocrine work-ups.

How it works

HOMA-IR = (fasting glucose mg/dL × fasting insulin µU/mL) / 405.

Key points

  • Cut-offs vary by population and assay (~2.5–2.9).
  • Requires true fasting samples.
  • Use trends and local references, not a universal threshold.

References

Worked calculation

The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.

Fasting glucose100 mg/dL
Fasting insulin10 µU/mL

→HOMA-IR2.47

  • Formula：(glucose mg/dL × insulin µU/mL) / 405
  • Interpretation：Average.
Verification & sources · governance
FAQ

Frequently asked questions

What are the limits and cautions when using HOMA-IR (Insulin Resistance)?
For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
Does HOMA-IR (Insulin Resistance) upload patient data? Where is it calculated?
Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
How is HOMA-IR (Insulin Resistance) calculated in practice? Can you show a worked example?
Inputs: Fasting glucose 100 mg/dL, Fasting insulin 10 µU/mL → Result: HOMA-IR 2.47（Formula: (glucose mg/dL × insulin µU/mL) / 405, Interpretation: Average.）
Related tools

Other tools