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🫀 Castelli Risk Index

UseSummarise the balance of atherogenic and protective cholesterol.

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SourceCastelli WP, et al. Circulation 1983

Runs locally in your browser (no PHI uploaded). For licensed clinicians — not a substitute for clinical judgement.
Stored on this device for revisit reminders

This-shift next steps

After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.

Scene next step
📋ASCVD / China-PAROpen scene pack →
Related scores
Matching pathway
🧭htn_emergencyOpen pathway →
Score + version; reference only — not a substitute for care · no HIS write

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Methodology · worked example, guidelines & full notes
Clinical takeaway

Complements absolute LDL and global risk scores.

When to use

Summarise the balance of atherogenic and protective cholesterol.

How it works

Castelli I = TC/HDL; Castelli II = LDL/HDL. Lower is better (TC/HDL ideally < 3.5).

Key points

  • Complements absolute LDL and global risk scores.
  • Higher ratios indicate greater atherogenic burden.
  • Not a standalone treatment trigger.

References

Worked calculation

The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.

Total cholesterol200 mg/dL
HDL cholesterol50 mg/dL
LDL cholesterol130 mg/dL

→Castelli I4.0

  • Castelli I (TC/HDL)：4.0
  • Castelli II (LDL/HDL)：2.6
  • Lower is better：TC/HDL < 4 (ideal < 3.5); higher ratios = greater atherogenic risk.
Verification & sources · governance
FAQ

Frequently asked questions

What are the limits and cautions when using Castelli Risk Index?
For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
Does Castelli Risk Index upload patient data? Where is it calculated?
Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
How is Castelli Risk Index calculated in practice? Can you show a worked example?
Inputs: Total cholesterol 200 mg/dL, HDL cholesterol 50 mg/dL, LDL cholesterol 130 mg/dL → Result: Castelli I 4.0（Castelli I (TC/HDL): 4.0, Castelli II (LDL/HDL): 2.6, Lower is better: TC/HDL < 4 (ideal < 3.5); higher ratios = greater atherogenic risk.）
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