🎗️ Cairo-Bishop Tumor Lysis Syndrome
UseSelect whether each of uric acid, potassium, phosphate, and calcium is abnormal, plus any clinical event; the…
SourceCoiffier B, et al. Guidelines for the management of pediatric and adult tumor lysis syndrome. J Cli…
This-shift next steps
After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.
Paste the link in Slack, Teams, X, or LinkedIn — the preview image comes from this page’s Open Graph card.
Methodology · worked example, guidelines & full notes
Laboratory TLS: ≥ 2 metabolic abnormalities in the time window.
When to use
Select whether each of uric acid, potassium, phosphate, and calcium is abnormal, plus any clinical event; the tool classifies no TLS, laboratory TLS, or clinical TLS.
How it works
Laboratory TLS = ≥2 metabolic abnormalities (threshold or ±25% from baseline) from 3 days before to 7 days after therapy. Clinical TLS = laboratory TLS + AKI, arrhythmia, or seizure.
Key points
- Laboratory TLS: ≥ 2 metabolic abnormalities in the time window.
- Clinical TLS: laboratory TLS plus a clinical event.
- Interpret against baseline values.
References
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Uric acid ≥476 μmol/L or ↑25% from baseline | Yes |
|---|---|
| Potassium ≥6.0 mmol/L or ↑25% | Yes |
| Phosphate ≥1.45 mmol/L (adult) or ↑25% | Yes |
| Calcium ≤1.75 mmol/L or ↓25% | Yes |
| Clinical event present (AKI / arrhythmia / seizure) | Yes |
→DeterminationClinical TLS
- Abnormal metabolic items：4 / 4
| Uric acid ≥476 μmol/L or ↑25% from baseline | No |
|---|---|
| Potassium ≥6.0 mmol/L or ↑25% | No |
| Phosphate ≥1.45 mmol/L (adult) or ↑25% | No |
| Calcium ≤1.75 mmol/L or ↓25% | No |
| Clinical event present (AKI / arrhythmia / seizure) | No |
→DeterminationNo TLS
- Abnormal metabolic items：0 / 4
Verification & sources · governance
FAQ
Frequently asked questions
- What are the limits and cautions when using Cairo-Bishop Tumor Lysis Syndrome?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- Does Cairo-Bishop Tumor Lysis Syndrome upload patient data? Where is it calculated?
- Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
- How is Cairo-Bishop Tumor Lysis Syndrome calculated in practice? Can you show a worked example?
- Inputs: Uric acid ≥476 μmol/L or ↑25% from baseline Yes, Potassium ≥6.0 mmol/L or ↑25% Yes, Phosphate ≥1.45 mmol/L (adult) or ↑25% Yes, Calcium ≤1.75 mmol/L or ↓25% Yes, Clinical event present (AKI / arrhythmia / seizure) Yes → Result: Determination Clinical TLS（Abnormal metabolic items: 4 / 4） Inputs: Uric acid ≥476 μmol/L or ↑25% from baseline No, Potassium ≥6.0 mmol/L or ↑25% No, Phosphate ≥1.45 mmol/L (adult) or ↑25% No, Calcium ≤1.75 mmol/L or ↓25% No, Clinical event present (AKI / arrhythmia / seizure) No → Result: Determination No TLS（Abnormal metabolic items: 0 / 4）